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轻度行为障碍对痴呆症临床试验的影响。

Dementia clinical trial implications of mild behavioral impairment.

机构信息

Centre for Research on Ageing,Health and Wellbeing,Research School of Population Health,The Australian National University,Canberra,Australia.

Department of Medicine (Neurology),Hurvitz Brain Sciences Research Program,Sunnybrook Research Institute,Sunnybrook HSC,University of Toronto,Toronto,Canada.

出版信息

Int Psychogeriatr. 2018 Feb;30(2):171-175. doi: 10.1017/S1041610218000042.

DOI:10.1017/S1041610218000042
PMID:29448970
Abstract

The World Alzheimer Report 2016 estimated that 47 million people are living with dementia worldwide (Alzheimer's Disease International, 2016). In the inaugural World Health Organization Ministerial Conference on Global Action against Dementia, six of the top ten research priorities were focused on prevention, identification, and reduction of dementia risk, and on delivery and quality of care for people with dementia and their carers (Shah et al., 2016). While the Lancet Neurology Commission has suggested that even minor advances to delay progression or ameliorate symptoms might have substantial financial and societal benefits (Winblad et al., 2016), advances have been slow.

摘要

《2016 年世界阿尔茨海默病报告》估计,全球有 4700 万人患有痴呆症(国际阿尔茨海默病协会,2016 年)。在首届世界卫生组织全球防治痴呆症部长级会议上,排名前十的研究重点中有六项聚焦于预防、识别和降低痴呆症风险,以及为痴呆症患者及其照护者提供护理和提高护理质量(Shah 等人,2016 年)。虽然《柳叶刀神经病学委员会》曾表示,即使是延缓疾病进展或改善症状的微小进展,也可能带来巨大的经济和社会效益(Winblad 等人,2016 年),但进展一直缓慢。

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