Fava G A, Kellner R, Lisansky J, Park S, Perini G I, Zielezny M
J Affect Disord. 1986 Jul-Aug;11(1):29-33. doi: 10.1016/0165-0327(86)90056-x.
Different methods of assessing depression and anxiety were tested in 20 patients suffering from a major depressive disorder with melancholia and 20 matched control subjects. Depressives were assessed before and after treatment with amitriptyline and normals were retested at the same interval. The scales used were: Paykel's Clinical Interview for Depression--which is an expanded version of the Hamilton Depression Rating Scale; the Brief Depression Rating Scale; and Symptom Questionnaire (SQ). All scales discriminated sensitively between patients and normals and the scores changed substantially with treatment. Except for the well-being subscales of the SQ, the scales showed an adequate test-retest reliability in normals. Although all scales were suitable for the measurement of depression, they differed in psychometric properties. For example, the Depression subscale of the SQ showed an unusually high test-retest reliability in normals, whereas the Contentment subscale was unreliable. Yet, the latter has been found to be highly sensitive in detecting differences between the effects of psychotropic drugs and placebo in drug trials, so it appears to measure sensitively a fleeting mood. The combined use of all three scales in patients with affective disorders yields information that might not be revealed if only one scale is used.
在20名患有伴有忧郁症的重度抑郁症患者和20名匹配的对照受试者中测试了评估抑郁和焦虑的不同方法。对抑郁症患者在接受阿米替林治疗前后进行评估，对正常受试者在相同间隔时间进行重新测试。使用的量表有：佩克尔抑郁临床访谈量表（这是汉密尔顿抑郁评定量表的扩展版本）；简易抑郁评定量表；以及症状问卷（SQ）。所有量表都能敏感地区分患者和正常受试者，并且分数随治疗有显著变化。除了症状问卷的幸福感分量表外，这些量表在正常受试者中显示出足够的重测信度。尽管所有量表都适用于测量抑郁，但它们在心理测量特性上有所不同。例如，症状问卷的抑郁分量表在正常受试者中显示出异常高的重测信度，而满足感分量表不可靠。然而，后者在药物试验中已被发现对检测精神药物和安慰剂效果之间的差异非常敏感，所以它似乎能敏感地测量一种短暂的情绪。在情感障碍患者中联合使用这三种量表可产生仅使用一种量表时可能无法揭示的信息。
