Pal Sitaram, Manjunath Bhanu, Ghorai Sujit, Sasmal Swarnendu
Syngenta Biosciences Private Limited, Research & Technology Centre, Santa Monica Works, Ilhas, Corlim, Goa, India.
Syngenta Biosciences Private Limited, Research & Technology Centre, Santa Monica Works, Ilhas, Corlim, Goa, India.
Alkaloids Chem Biol. 2018;79:71-137. doi: 10.1016/bs.alkal.2017.12.002.
Benzoxazole alkaloids exhibit a diverse array of structures and interesting biological activities. In spite of the extensive research done on the synthesis and biology, till date there is no concise update on this class of alkaloids. This chapter summarizes the literature on benzoxazole alkaloids till March 2017, which covers their isolation, characterization, possible biosynthetic origins, biological activities, and major synthetic approaches. These alkaloids have been broadly classified in the context of their sources, namely (i) fungal origin, (ii) marine origin, and (iii) plant origin.
苯并恶唑生物碱具有多种多样的结构和有趣的生物活性。尽管在其合成和生物学方面已经进行了广泛的研究,但迄今为止,关于这类生物碱还没有简明的最新综述。本章总结了截至2017年3月关于苯并恶唑生物碱的文献,内容涵盖它们的分离、表征、可能的生物合成起源、生物活性以及主要的合成方法。这些生物碱已根据其来源大致分为以下几类:(i)真菌来源,(ii)海洋来源,以及(iii)植物来源。