邻苯二酚、苄醇/苄基甲基醚与醋酸铵的一锅多组分偶联反应用于合成苯并恶唑。
One-Pot Multicomponent Coupling Reaction of Catechols, Benzyl Alcohols/Benzyl Methyl Ethers, and Ammonium Acetate toward Synthesis of Benzoxazoles.
作者信息
Aboonajmi Jasem, Panahi Farhad, Sharghi Hashem
机构信息
Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran.
出版信息
ACS Omega. 2021 Aug 18;6(34):22395-22399. doi: 10.1021/acsomega.1c03207. eCollection 2021 Aug 31.
Abstract
The multicomponent coupling reaction of catechol, ammonium acetate, and benzyl alcohol/benzyl methyl ether in the presence of a Fe(III) catalyst precursor afforded benzoxazole derivatives in good to excellent yields. The notable features of this protocol are abundant availability of the catalyst system, large-scale synthesis, high diversity, and high yields of products.
摘要
在铁（III）催化剂前体存在下，邻苯二酚、醋酸铵与苯甲醇/苄基甲基醚的多组分偶联反应以良好至优异的产率得到苯并恶唑衍生物。该方法的显著特点是催化剂体系易于获得、可大规模合成、多样性高且产物产率高。
Zotero 插件