Biomechanics Labs of Orthopaedics Institute, Tianjin Hospital, Tianjin, People's Republic of China; Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China; Tianjin Hospital, Tianjin University, Tianjin, People's Republic of China.
Biomechanics Labs of Orthopaedics Institute, Tianjin Hospital, Tianjin, People's Republic of China; Tianjin Hospital, Tianjin University, Tianjin, People's Republic of China.
J Arthroplasty. 2018 Jun;33(6):1972-1978.e4. doi: 10.1016/j.arth.2017.12.042. Epub 2018 Jan 11.
Total knee arthroplasty (TKA) is accompanied by moderate-to-severe postoperative pain. Postoperative pain will hamper functional recovery and lower patients' satisfaction with surgery. Recently, periarticular local infiltration analgesia (LIA) has been widely used in TKA. However, there is no definite answer as to the efficacy and safety of LIA compared with femoral nerve block (FNB).
Randomized controlled trials about relevant studies were searched from PubMed (1996 to July 2017), Embase (1980 to July 2017), and Cochrane Library (CENTRAL, July 2017). Ten studies which compared LIA with FNB methods were included in our meta-analysis.
Ten studies containing 950 patients met the inclusion criteria. Our pooled data indicated that LIA was as effective as the FNB in terms of visual analog scale score for pain at 24 hours (P = .52), 48 hours (P = .36), and 72 hours (P = .27), and total morphine consumption (P = .27), range of motion (P = .45), knee society score (P = .51), complications (P = .81), and length of hospital stay (P = .75).
Our current meta-analysis results demonstrated that there were no differences in efficacy between the FNB and LIA method.
全膝关节置换术（TKA）伴有中重度术后疼痛。术后疼痛会妨碍功能恢复，降低患者对手术的满意度。最近，关节周围局部浸润镇痛（LIA）已广泛应用于 TKA。然而，LIA 与股神经阻滞（FNB）相比的疗效和安全性尚无明确答案。
从 PubMed（1996 年至 2017 年 7 月）、Embase（1980 年至 2017 年 7 月）和 Cochrane Library（CENTRAL，2017 年 7 月）中检索到关于相关研究的随机对照试验。我们的荟萃分析纳入了 10 项比较 LIA 与 FNB 方法的研究。
符合纳入标准的研究有 10 项，共包含 950 名患者。我们的汇总数据表明，在术后 24 小时（P =.52）、48 小时（P =.36）和 72 小时（P =.27）的疼痛视觉模拟评分、总吗啡消耗量（P =.27）、关节活动度（P =.45）、膝关节协会评分（P =.51）、并发症（P =.81）和住院时间（P =.75）方面，LIA 与 FNB 同样有效。
我们当前的荟萃分析结果表明，FNB 与 LIA 方法在疗效方面没有差异。
