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噪声性听力损失(NIHL)的病因及其与II型糖尿病听力测定结果的症状相关性

Etiology of Noise-Induced Hearing Loss (NIHL) and its Symptomatic Correlation with Audiometry Observations in Type II Diabetes.

作者信息

Yadav Meena K, Yadav K S

机构信息

1School of Ayurveda, D Y Patil University, Navi Mumbai, Maharashtra India.

2School of Medicine, D Y Patil University, Navi Mumbai, Maharashtra India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2018 Mar;70(1):137-144. doi: 10.1007/s12070-017-1188-0. Epub 2017 Sep 6.

Abstract

Type II diabetic mellitus (DM) is a chronic metabolic disease that impairs normal insulin production and glucose transport to the liver and muscles. In the India, about 1-5% population suffer from diabetes or related complication. So there is need to cure this disease. DM chronic auditory complications may include spiral ganglia atrophy, degeneration of the vestibulocochlear nerve myelin sheath, reduction of the number of spiral lamina nerve fibres, and thickening of the capillary walls of the stria vascularis and small arteries. This study aims to know the incidence of common parameters, blood sugar levels, levels of lipids and the hearing thresholds of individuals. It is a Noise-Induced Hearing Loss research study featuring hearing impairment in transport workers diagnosed as type II diabetic. All individuals were interviewed by various questioners related to listening ability of subjects and underwent a physical examination, blood investigations and audiometry. Hearing impairment was more prevalent among adults with diabetes. Sensory neuron hearing loss is predominant in both study groups. Mixed Bilateral Hearing Loss showed significant value in (>.001) by audiometry. The percentage of hearing loss in diabetes (ranges 5.3-28.1%) and in non-diabetics (ranges 3.4-24.1%) and risk factors in diabetes (ranges 22.8-35.1%) over nondiabetics (ranges 17.2-20.1%) which is eye opener. The correlation between type II diabetes and hearing impairment was independent of known risk factors for hearing impairment, such as noise exposure, build-up wax, ototoxic medication, smoking, tobacco chewing etc.

摘要

2型糖尿病(DM)是一种慢性代谢性疾病,会损害正常胰岛素分泌以及肝脏和肌肉对葡萄糖的转运。在印度,约1-5%的人口患有糖尿病或相关并发症。因此,需要治愈这种疾病。糖尿病的慢性听觉并发症可能包括螺旋神经节萎缩、前庭蜗神经髓鞘变性、螺旋板神经纤维数量减少以及血管纹和小动脉毛细血管壁增厚。本研究旨在了解常见参数、血糖水平、血脂水平以及个体听力阈值的发生率。这是一项关于噪声性听力损失的研究,以被诊断为2型糖尿病的运输工人的听力损伤为特征。所有个体都接受了与听力能力相关的各种问卷调查,并进行了体格检查、血液检查和听力测定。听力损伤在糖尿病成年人中更为普遍。两个研究组中感觉神经元性听力损失占主导。混合性双侧听力损失通过听力测定显示出显著值(>0.001)。糖尿病患者的听力损失百分比(范围为5.3-28.1%)和非糖尿病患者(范围为3.4-24.1%)以及糖尿病患者的危险因素(范围为22.8-35.1%)高于非糖尿病患者(范围为17.2-20.1%),这令人警醒。2型糖尿病与听力损伤之间的相关性独立于已知的听力损伤危险因素,如噪声暴露、耳垢堆积、耳毒性药物、吸烟、嚼烟草等。

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本文引用的文献

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Hearing loss prevalence in patients with diabetes mellitus type 1.1 型糖尿病患者的听力损失患病率。
Braz J Otorhinolaryngol. 2012 Jun;78(3):105-15. doi: 10.1590/S1808-86942012000300018.
2
Auditory acuity in type 2 diabetes mellitus.2型糖尿病患者的听觉敏锐度
Int J Diabetes Dev Ctries. 2008 Oct;28(4):114-20. doi: 10.4103/0973-3930.45270.
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Laryngoscope. 2009 Sep;119(9):1788-96. doi: 10.1002/lary.20570.
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Braz J Otorhinolaryngol. 2005 Sep-Oct;71(5):633-8. doi: 10.1016/s1808-8694(15)31268-4. Epub 2006 Mar 31.
8
Diabetes mellitus as etiological factor of hearing loss.糖尿病作为听力损失的病因
Braz J Otorhinolaryngol. 2005 Mar-Apr;71(2):208-14. doi: 10.1016/s1808-8694(15)31312-4. Epub 2005 Aug 2.
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Cognitive P300 potential in subjects with Diabetes Mellitus.糖尿病患者的认知P300电位
Braz J Otorhinolaryngol. 2005 Mar-Apr;71(2):202-7. doi: 10.1016/s1808-8694(15)31311-2. Epub 2005 Aug 2.
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Pathophysiology of coronary artery disease.冠状动脉疾病的病理生理学
Circulation. 2005 Jun 28;111(25):3481-8. doi: 10.1161/CIRCULATIONAHA.105.537878.

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