Barroso Catarina, Correia-Pinto Jorge
Department of Pediatric Surgery, Hospital de Braga, Braga, Portugal.
School of Medicine, University of Minho, Braga, Portugal.
Eur J Pediatr Surg. 2018 Apr;28(2):141-147. doi: 10.1055/s-0038-1632374. Epub 2018 Feb 19.
Although improvements have been made, the management of congenital diaphragmatic hernia (CDH) remains a major challenge for perinatologists and neonatal surgeons. Many aspects of the disease remain unknown and, being a rare entity, evidence-based data are hard to find. Surgical morbidity is considerable and affects long-term quality of life. Perioperative complications have been reviewed focusing on thoracoscopic repair. Intraoperative acidosis was more severe during thoracoscopy when compared with open surgery (OS), though it is possible that later neurodevelopment was not affected. Even so, strategies have been outlined to reduce acidosis, such as decreasing carbon dioxide (CO) insufflation after reduction of the herniated viscera into the abdomen is complete. The risk of pleural complications decreased after introduction of gentle ventilation techniques and minimally invasive surgery (MIS); thus, the use of a prophylactic intraoperative thoracic tube is not routinely required. Recurrence rate was higher in large CDH and following MIS repair. Technical demands play an important role, therefore, in avoiding complications; every step of the OS technique must be strictly accomplished. In large defects, the use of prosthetic patch might reduce recurrence rate, even by MIS repair, once again only if technical demands are overcome with meticulous rules of suturing. Thoracoscopy significantly reduced the incidence of bowel obstruction and recovery time and improved cosmesis. The best approach of CDH is yet to be found, and it goes far beyond the management of perioperative complications. Meanwhile randomized controlled studies, namely on the outcome of thoracoscopic repair, are required to inform further practice.
尽管已有改进,但先天性膈疝(CDH)的管理对围产医学专家和新生儿外科医生来说仍然是一项重大挑战。该疾病的许多方面仍不为人知,而且作为一种罕见病症,很难找到循证数据。手术发病率相当高,会影响长期生活质量。已针对胸腔镜修补术对围手术期并发症进行了综述。与开放手术(OS)相比,胸腔镜检查期间术中酸中毒更为严重,不过后期神经发育可能未受影响。即便如此,已制定了减少酸中毒的策略,比如在将疝出的内脏完全还纳入腹腔后减少二氧化碳(CO)充气。引入轻柔通气技术和微创手术(MIS)后,胸膜并发症的风险降低;因此,通常不需要预防性术中放置胸管。大型CDH以及MIS修复术后复发率更高。因此,技术要求在避免并发症方面起着重要作用;OS技术的每一步都必须严格完成。在大的缺损中,使用人工补片可能会降低复发率,即使是通过MIS修复,前提是只有在通过细致的缝合规则克服技术要求的情况下才行。胸腔镜检查显著降低了肠梗阻的发生率和恢复时间,并改善了美观效果。CDH的最佳治疗方法尚未找到,而且这远远超出围手术期并发症的管理范畴。与此同时,需要进行随机对照研究,即关于胸腔镜修复结果的研究,以便为进一步的实践提供依据。