Pulmonary, Critical Care and Sleep Medicine Section, Department of Medicine, Baylor College of Medicine, Houston, Texas.
J Clin Sleep Med. 2018 Mar 15;14(3):483-484. doi: 10.5664/jcsm.7008.
This is a rare case of non-24-hour sleep-wake rhythm disorder in a sighted male with normal functioning. The patient, a 23-year-old doctorate graduate student, presented with difficulty falling asleep and excessive daytime sleepiness. He reported variable sleep and wake times. Overnight baseline polysomnography was unremarkable and his Multiple Sleep Latency Test was significant for short mean sleep latency. Sleep diary and actigraphy were obtained, which demonstrated a pattern of delaying of sleep and wake times each day. He had excellent symptom response to nightly melatonin.
这是一例罕见的视力正常男性非 24 小时睡眠-觉醒节律障碍病例。患者为 23 岁博士生，表现为入睡困难和日间过度嗜睡。他报告说睡眠时间和觉醒时间不规律。夜间基线多导睡眠图无明显异常，多次睡眠潜伏期试验显示平均睡眠潜伏期短。睡眠日记和活动记录仪记录到每天睡眠和觉醒时间逐渐延迟的模式。他对夜间褪黑素治疗有很好的症状反应。
