Department of Pediatrics, Chungnam National University College of Medicine, Daejeon, South Korea.
Sleep Med. 2018 Feb;42:47-52. doi: 10.1016/j.sleep.2017.10.015. Epub 2017 Dec 13.
Epidemiologic studies have found an association between sleep duration and obesity. However, the relationship between sleep duration and metabolic body size phenotype in children and adolescents remains unknown.
In this cross-sectional study, 3650 participants (1946 boys and 1704 girls) from the Korean National Health and Nutrition Examination Survey 2007-2012 were classified into four phenotypes according to body mass index and metabolic heath status based on the definition of metabolic syndrome by NCEP-ATP III or the International Diabetes Federation. The four phenotypes were: metabolically healthy normal weight (MHNW), metabolically unhealthy normal weight (MUNW), metabolically healthy overweight (MHO), and metabolically unhealthy overweight (MUO). The associations between the four metabolic body size phenotypes and sleep duration, categorized as very short (≤5 h), short (6-7 h), normal (8-10 h), or long (≥11 h), were evaluated.
Sleep duration was shorter in the MUO group (7.0 ± 1.5 h) than in the MHNW (7.3 ± 1.4 h) or MUNW (7.8 ± 1.6 h) groups. After adjusting for age, sex, household income, and physical activity, compared with a normal sleep duration, very short sleep duration (≤5 h) was associated with a higher prevalence of being overweight/obese (26.4% vs 17.4%, p = 0.001), lower risk of being MHNW (0.711 (0.538-0.940), p = 0.017) or MUNW (0.478 (0.237-0.962), p = 0.039), and higher risk of being MHO (1.702 (1.193-2.428), p = 0.003). By contrast, long sleep duration (≥11 h) was associated with a higher risk of being MUNW (2.581 (1.124-5.928), p = 0.025).
Sleep duration may be independently associated with metabolic body size phenotype in children and adolescents.
流行病学研究发现睡眠时长与肥胖之间存在关联。然而，儿童和青少年的睡眠时长与代谢体型表型之间的关系尚不清楚。
在这项横断面研究中，根据 NCEP-ATP III 或国际糖尿病联合会对代谢综合征的定义，将 2007-2012 年韩国国家健康和营养检查调查中的 3650 名参与者（1946 名男孩和 1704 名女孩）分为四类表型，依据的是身体质量指数和代谢健康状况。这四种表型是：代谢健康正常体重（MHNW）、代谢不健康正常体重（MUNW）、代谢健康超重（MHO）和代谢不健康超重（MUO）。评估了四种代谢体型表型与睡眠时长（分为极短（≤5 小时）、短（6-7 小时）、正常（8-10 小时）或长（≥11 小时））之间的关系。
MUO 组的睡眠时长更短（7.0±1.5 小时），低于 MHNW（7.3±1.4 小时）或 MUNW（7.8±1.6 小时）组。在调整年龄、性别、家庭收入和体力活动后，与正常睡眠时长相比，极短睡眠时长（≤5 小时）与超重/肥胖的发生率更高（26.4%比 17.4%，p=0.001）、代谢健康正常体重（0.711（0.538-0.940），p=0.017）或代谢不健康正常体重（0.478（0.237-0.962），p=0.039）的可能性更低，代谢健康超重（1.702（1.193-2.428），p=0.003）的可能性更高。相比之下，长睡眠时长（≥11 小时）与代谢不健康正常体重的风险增加相关（2.581（1.124-5.928），p=0.025）。
睡眠时长可能与儿童和青少年的代谢体型表型独立相关。
