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自述的中风病史与长期居住在空气污染源附近的关系:黎巴嫩一项全国性流行病学研究的结果。

Self-reported history of stroke and long-term living conditions near air pollution sources: results of a national epidemiological study in Lebanon.

机构信息

Faculty of Medical Sciences, Lebanese University, Hadath, Lebanon.

Faculty of Pharmacy, Lebanese University, Hadath, Lebanon.

出版信息

Environ Monit Assess. 2018 Feb 20;190(3):153. doi: 10.1007/s10661-018-6545-2.

Abstract

Stroke is a disease related to high mortality and morbidity, particularly in developing countries. Some studies have linked self-reported indoor and outdoor pollution to stroke and mini-stroke, while some others showed no association. Our objective was to assess this association in Lebanon, a Middle Eastern developing country. A national cross-sectional study was conducted all over Lebanon. In addition to self-reported items of pollution exposure, we assessed potential predictors of stroke and mini-stroke, including sociodemographic characteristics, self-reported health information, and biological measurements. Moreover, we assessed dose-effect relationship of pollution items in relation with stroke. Self-reported indoor pollution exposure was associated with stroke and mini-stroke, with or without taking biological values into account. Moreover, we found a dose-effect relationship of exposure with risk of disease, but this effect did not reach statistical significance after adjustment for sociodemographics and biological characteristics. No association was found for any outdoor pollution item. Although additional studies would be necessary to confirm these findings, sensitizing the population about the effect of pollution on chronic diseases, working on reducing pollution, and improving air quality should be implemented to decrease the burden of the disease on the population and health system.

摘要

中风是一种与高死亡率和高发病率相关的疾病,尤其是在发展中国家。一些研究将自我报告的室内和室外污染与中风和小中风联系起来,而另一些研究则没有发现这种关联。我们的目的是在黎巴嫩这个中东发展中国家评估这种关联。我们在黎巴嫩全国范围内进行了一项横断面研究。除了自我报告的污染暴露项目外,我们还评估了中风和小中风的潜在预测因素,包括社会人口统计学特征、自我报告的健康信息和生物学测量值。此外,我们还评估了污染项目与中风的剂量-效应关系。自我报告的室内污染暴露与中风和小中风有关,无论是否考虑生物值。此外,我们发现暴露与疾病风险之间存在剂量-效应关系,但在调整社会人口统计学和生物学特征后,这种效应没有达到统计学意义。任何室外污染项目都没有发现关联。尽管需要进一步的研究来证实这些发现,但应该提高公众对污染对慢性病的影响的认识,努力减少污染并改善空气质量,以减轻疾病对人口和卫生系统的负担。

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