[The efficacy of cocarnit in diabetic neuropathy].
作者信息
Kotov S V, Isakova E V, Leidvoll V Yu, Belova Yu A, Volchenkova T V, Borodin A V, Shvedov V A
机构信息
Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia.
出版信息
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(1):37-42. doi: 10.17116/jnevro20181181137-42.
AIM
To study the efficacy of the complex therapy, including cocarnit (group B vitamins, triphosadenine and nicotinamide), of diabetic neuropathy.
MATERIAL AND METHODS
Forty-one patients with diabetes mellitus type 2 and distal symmetric sensorimotor polyneuropathy were examined. Patients were divided into 2 groups. Patients of the main group (n=26) received complex therapy, including cocarnit, and patients of the comparison group (n=15) received standard treatment.
RESULTS AND CONCLUSION
The positive dynamics based on the VAS (р=0.0001), TSS (р=0.0001), NSS (р=0.001), NDS (р=0.0431), SF-36 (р=0.0008), electroneuromyographic results and glycated hemoglobin levels was observed in the main group. In patients of the comparison group, the positive dynamics was instable; the scores of clinical scales did not reach statistical significance. The results suggest the use of cocarnit in the complex treatment of patients with diabetic neuropathy.
Zotero 插件