Chutko L S, Kornishina T L, Surushkina S Yu, Yakovenko E A, Anisimova T I, Volov M B
Bekhtereva Institute of Human Brain Russian Academy of Sciences, St. Petersburg, Russia.
Bekhtereva Institute of Human Brain Russian Academy of Sciences, St. Petersburg, Russia; St. Peterburg State Pediatric Medical University, St. Peterburg, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(1):43-49. doi: 10.17116/jnevro20181181143-49.
To study clinical and pathophysiological symptoms of autonomic dysfunction syndrome in children and adolescents and assess the efficacy of its treatment with nooclerin.
Fifty-three patients, aged from 10 to 15 years, with autonomic dysfunction syndrome were examined. All patients underwent neurological examination, assessment with the A.M. Vein's questionnaire of autonomic disorders, the 10 point Visual Analogous scale for headache and fatigue, the Spielberger-Khanin scale for anxiety, Kerdo index, Hildebrandt's coefficient, electrocardiography with clinoorthostatic test, electroencephalography, and TOVA psychophysiological test.
The signs of the asthenic-autonomic syndrome were characteristic of the clinical picture of disease. EEG results demonstrated the deficit of activation effects, predominance of synchronized effects of thalamic structures which led to the insufficient activation of cortical structures. These data support the high efficacy of nooclerin.
研究儿童和青少年自主神经功能障碍综合征的临床和病理生理症状，并评估诺克洛林对其治疗的疗效。
对53例年龄在10至15岁的自主神经功能障碍综合征患者进行检查。所有患者均接受了神经系统检查、使用A.M. 韦恩自主神经障碍问卷进行评估、用于评估头痛和疲劳的10分视觉模拟量表、用于评估焦虑的斯皮尔伯格 - 卡宁量表、凯尔多指数、希尔德布兰特系数、临床直立倾斜试验心电图、脑电图以及TOVA心理生理测试。
虚弱 - 自主神经综合征的体征是该疾病临床症状的特征。脑电图结果显示激活效应不足，丘脑结构同步效应占主导，导致皮质结构激活不足。这些数据支持诺克洛林具有高效性。
