Burton B K
Am J Obstet Gynecol. 1986 Nov;155(5):984-6. doi: 10.1016/0002-9378(86)90330-3.
The ratio of amniotic fluid acetylcholinesterase to pseudocholinesterase was determined by scanning densitometry on 43 amniotic fluid samples with positive acetylcholinesterase associated with open fetal defects. The mean ratio was 0.587 (range 0.204 to 0.979) in 21 amniotic fluid samples from pregnancies affected with open spina bifida and 0.052 (range 0.026 to 0.075) in 12 pregnancies affected with ventral wall defects. These data confirm previous observations and indicate that scanning densitometry of electrophoretic gels is a useful method for distinguishing between open spina bifida and ventral wall defects in the fetus.
通过扫描密度计测定了43份与开放性胎儿缺陷相关的乙酰胆碱酯酶呈阳性的羊水样本中羊水乙酰胆碱酯酶与假性胆碱酯酶的比值。21份来自患有开放性脊柱裂妊娠的羊水样本中，平均比值为0.587（范围为0.204至0.979）；12份患有腹壁缺陷妊娠的羊水样本中，平均比值为0.052（范围为0.026至0.075）。这些数据证实了先前的观察结果，并表明电泳凝胶的扫描密度计法是区分胎儿开放性脊柱裂和腹壁缺陷的一种有用方法。
