Dupont M, Vallet B, Brun A, Boulot P, Demaille J
Laboratoire de Biochimie génétique, Hôpital Arnaud-de-Villeneuve, Montpellier, France.
Biol Neonate. 1995;67(4):244-7. doi: 10.1159/000244171.
The quantification of 'faint-positive' cholinesterases in amniotic fluid was performed in 40 patients with positive acetylcholinesterase (AchE) tests. Fetuses with anencephaly and open spina bifida presented an AchE/butyrylcholinesterase (A/B) ratio of more than 0.3 with clearly dense bands. Fetuses with gastroschisis showed a 'faint-positive' AchE band (A/B < 0.3). In 5 fetuses (1 teratoma, 3 open spina bifida, 1 unaffected) we found faint AchE and butyrylcholinesterase bands.
对40例乙酰胆碱酯酶（AchE）检测呈阳性的患者的羊水进行了“弱阳性”胆碱酯酶的定量分析。无脑儿和开放性脊柱裂胎儿的AchE/丁酰胆碱酯酶（A/B）比值大于0.3，条带明显浓密。腹裂胎儿显示出“弱阳性”AchE条带（A/B < 0.3）。在5例胎儿（1例畸胎瘤、3例开放性脊柱裂、1例正常）中，我们发现了微弱的AchE和丁酰胆碱酯酶条带。
