Tonyali Senol, Yilmaz Mehmet
Department of Urology, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey.
Curr Urol. 2017 Nov;11(1):1-3. doi: 10.1159/000447186. Epub 2017 Nov 30.
BACKGROUND/AIMS: Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a debilitating disease characterized with urgency, frequency, and pelvic pain affecting especially women. Sexual dysfunction in female patients with IC/BPS consists of dyspareunia, altered sexual desire and orgasm frequency and insufficient lubrication is reported to negatively affect the patient's quality of life. In the present study, we aimed to determine the association between IC/BPS and sexual dysfunction and improvement in sexual dysfunction related to given treatments.
A PubMed/Medline and EMBASE search was conducted using keywords: "interstitial cystitis", "sexual dysfunction", and "bladder pain syndrome".
Several studies have been conducted to determine the relation between IC/BPS and sexual dysfunction. And also limited studies focusing on IC/BPS specific treatments reported significant improvements in sexual function after either oral or intravesical treatment. However, given the used different questionnaires, study protocols, patient characteristics, previous treatments and follow-up period, it is not possible to make a head-to-head comparison of the treatment effects on sexual function. Further, randomized controlled studies are needed to confirm these results and make a comparison between effects of various treatment modalities on sexual functioning in IC/BPS.
背景/目的：间质性膀胱炎（IC）/膀胱疼痛综合征（BPS）是一种使人衰弱的疾病，其特征为尿急、尿频和盆腔疼痛，尤其影响女性。IC/BPS女性患者的性功能障碍包括性交困难、性欲和性高潮频率改变，且据报道润滑不足会对患者的生活质量产生负面影响。在本研究中，我们旨在确定IC/BPS与性功能障碍之间的关联，以及特定治疗相关的性功能障碍改善情况。
使用关键词“间质性膀胱炎”、“性功能障碍”和“膀胱疼痛综合征”在PubMed/Medline和EMBASE数据库中进行检索。
已经开展了多项研究来确定IC/BPS与性功能障碍之间的关系。此外，针对IC/BPS特定治疗的有限研究报告称，口服或膀胱内治疗后性功能有显著改善。然而，鉴于使用的问卷、研究方案、患者特征、既往治疗和随访期不同，无法对性功能的治疗效果进行直接比较。此外，需要随机对照研究来证实这些结果，并比较各种治疗方式对IC/BPS性功能的影响。
