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前列腺切除术后的生活质量与手术类型及神经保留程度的关系

Quality of Life Following Prostatectomy as a Function of Surgery Type and Degree of Nerve Sparing.

作者信息

Strassberg Donald S, Zavodni Suzanne M, Gardner Paul, Dechet Christopher, Stephenson Robert A, Sewell Kelsey K

机构信息

Department of Psychology, University of Utah, Salt Lake City, Utah, USA.

Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.

出版信息

Curr Urol. 2017 Nov;11(1):16-20. doi: 10.1159/000447189. Epub 2017 Nov 30.

DOI:10.1159/000447189
PMID:29463972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5814780/
Abstract

OBJECTIVES

To compare robotic-assisted laparoscopic prostatectomy with conventional retropubic radical prostatectomy in maintaining pre-surgery levels of urinary and sexual functioning and to evaluate the efficacy of nerve sparing in prostatectomies in protecting urinary functioning.

MATERIAL AND METHODS

Patients (n = 385) receiving both surgical procedures were surveyed prior to surgery. Multiple measures, including the Expanded Prostate Cancer Index Composite, the Sexual Health Inventory for Men, and the International Prostate Symptom Score, assessed sexual and urinary function at an average of 12 months post-surgery.

RESULTS

Across multiple measures, while controlling for pre-surgical sexual functioning, robotic-assisted surgery did not offer an advantage in maintaining sexual or urinary function an average of a year following the prostatectomy. Bilateral nerve sparing offered a strong and reliable advantage in the maintenance of sexual function, but not so regarding urinary function.

CONCLUSION

While robotic-assisted prostatectomies may offer a number of medical advantages over open procedures, we found no significant effect on important quality of life outcomes associated with the technique.

摘要

目的

比较机器人辅助腹腔镜前列腺切除术与传统耻骨后根治性前列腺切除术在维持术前泌尿和性功能水平方面的差异,并评估前列腺切除术中保留神经对保护泌尿功能的疗效。

材料与方法

对接受这两种手术的患者(n = 385)在手术前进行调查。采用多种测量方法,包括扩展前列腺癌指数综合评分、男性性健康量表和国际前列腺症状评分,在术后平均12个月时评估性功能和泌尿功能。

结果

在多种测量方法中,在控制术前性功能的情况下,机器人辅助手术在前列腺切除术后平均一年维持性功能或泌尿功能方面并无优势。双侧保留神经在维持性功能方面具有显著且可靠的优势,但在泌尿功能方面并非如此。

结论

虽然机器人辅助前列腺切除术可能比开放手术具有一些医学优势,但我们发现该技术对与生活质量相关的重要结果没有显著影响。

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本文引用的文献

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Eur Urol. 2017 Mar;71(3):330-336. doi: 10.1016/j.eururo.2016.11.015. Epub 2016 Nov 22.
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Patient reported functional outcomes following robotic-assisted (RARP), laparoscopic (LRP), and open radical prostatectomies (ORP).患者报告的机器人辅助根治性前列腺切除术(RARP)、腹腔镜根治性前列腺切除术(LRP)和开放性根治性前列腺切除术(ORP)后的功能结局。
Ir J Med Sci. 2017 Nov;186(4):835-840. doi: 10.1007/s11845-016-1522-7. Epub 2016 Oct 28.
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Global Incidence and Mortality for Prostate Cancer: Analysis of Temporal Patterns and Trends in 36 Countries.全球前列腺癌发病率和死亡率:36 个国家时间模式和趋势分析。
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Factors Affecting Quality of Life at Different Intervals After Treatment of Localized Prostate Cancer: Unique Influence of Treatment Decision Making Satisfaction, Personality and Sexual Functioning.治疗局限性前列腺癌后不同时间点生活质量的影响因素:治疗决策满意度、个性和性功能的独特影响。
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