Gerlegiz Ege Nur Atabey, Öztürk Demet, Gürşen Ceren, Akbayrak Türkan, Özgül Serap
Department of Fundamental Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, 06100, Samanpazari, Ankara, Turkey.
J Cancer Surviv. 2025 Aug 28. doi: 10.1007/s11764-025-01882-6.
Prostate cancer is the second most commonly diagnosed malignancy in men worldwide. Post-prostatectomy urinary incontinence (PP-UI) is a common and distressing complication that significantly reduces quality of life in prostate cancer survivors. This systematic review aimed to evaluate the effectiveness of structured and supervised pelvic floor muscle training (PFMT), initiated after confirmed pelvic floor muscle activation, delivered pre- or postoperatively, with or without biofeedback (BF), on symptom severity and continence-related quality of life.
A comprehensive search of MEDLINE and Web of Science was conducted in December 2024. Twenty randomized controlled trials (RCTs) involving 2444 participants met inclusion criteria. All studies confirmed correct pelvic floor muscle contraction prior to intervention and implemented structured, supervised PFMT protocols. Risk of bias was assessed using the Cochrane RoB 2.0 tool, and study quality was evaluated using the GRADE framework. Due to heterogeneity in interventions and outcomes, a narrative synthesis was performed.
Thirteen of the twenty RCTs (65%) reported significant improvements in continence recovery and symptom severity with structured and supervised PFMT. Early initiation, higher training intensity, anterior compartment-focused training, and use of BF were associated with greater benefits. However, protocol and outcome variability limited consistency across studies.
Structured and supervised PFMT based on confirmed muscle activation is a key component of effective PP-UI management. Early, intensive training under therapist guidance is likely to accelerate recovery and enhance continence outcomes.
Targeted PFMT programs with confirmed muscle activation and professional supervision provide a safe, non-invasive, and potentially effective strategy to improve urinary continence and overall quality of life after prostate cancer treatment.
PROSPERO ID: CRD42023387493.
前列腺癌是全球男性中第二常见的确诊恶性肿瘤。前列腺切除术后尿失禁(PP - UI)是一种常见且令人苦恼的并发症,会显著降低前列腺癌幸存者的生活质量。本系统评价旨在评估在确认盆底肌肉激活后开始的、术前或术后进行的、有或无生物反馈(BF)的结构化和监督性盆底肌肉训练(PFMT)对症状严重程度和与控尿相关生活质量的有效性。
2024年12月对MEDLINE和科学网进行了全面检索。20项涉及2444名参与者的随机对照试验(RCT)符合纳入标准。所有研究在干预前均确认了正确的盆底肌肉收缩,并实施了结构化、监督性的PFMT方案。使用Cochrane RoB 2.0工具评估偏倚风险,并使用GRADE框架评估研究质量。由于干预措施和结果存在异质性,进行了叙述性综合分析。
20项RCT中的13项(65%)报告称,结构化和监督性PFMT使控尿恢复和症状严重程度有显著改善。早期开始、更高的训练强度、以前部区域为重点的训练以及使用BF与更大的益处相关。然而,方案和结果的变异性限制了各研究之间的一致性。
基于确认的肌肉激活进行结构化和监督性PFMT是有效管理PP - UI的关键组成部分。在治疗师指导下进行早期、强化训练可能会加速恢复并改善控尿结果。
经确认肌肉激活并由专业人员监督的针对性PFMT计划为改善前列腺癌治疗后的尿失禁和整体生活质量提供了一种安全、无创且可能有效的策略。
PROSPERO编号:CRD42023387493。