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埃塞俄比亚北部门诊糖尿病诊所2型糖尿病患者的糖尿病目标达成情况及其决定因素

Achievements of Diabetes Goals and Their Determinants in Type 2 Diabetic Patients Attending Outpatient Diabetic Clinic in Northern Ethiopia.

作者信息

Belay Ezra, Abera Abel, Mehari Aman, Gebremeskel Gidey, Endrias Asrat, Endris Kedir

机构信息

Department of Medical Biochemistry, College of Health Sciences, Mekelle University, 1871 Mekelle, Ethiopia.

Department of Nursing, College of Health Sciences, Mekelle University, 1871 Mekelle, Ethiopia.

出版信息

Int J Chronic Dis. 2017;2017:5713187. doi: 10.1155/2017/5713187. Epub 2017 Dec 31.

Abstract

BACKGROUND

The aim of this study was to assess target diabetic goal achievements and to explore variables associated with them.

METHODS

A cross-sectional study was conducted between December 2015 and April 2016 on 188 type 2 diabetic patients attending Ayder Referral Hospital's outpatient diabetic clinic. Glycemic control was assessed using fasting plasma glucose values and total cholesterol and triglyceride were used to evaluate lipid profiles. Bivariate and multivariate logistic regression analyses were done to identify factors associated with poor glycemic control, hypertension, and dyslipidemia.

RESULT

Mean duration of diabetes was 6.5 years. Combined glycemic, lipid, and blood pressure targets were achieved only in 8.5% of the participants. More males achieved combined targets than females. Separately, while above two-thirds of the patients had poor glycemic control (67%), more than half of the participants have had poor lipid (58.5%) and blood pressure (52.1%) control. A significant portion of the patients (68.1%) had also comorbidities other than hyperglycemia. In bivariate and multivariate analyses, longer duration of diabetes disease (AOR: 3.4; = 0.013) and marked month to month fasting plasma glucose (FPG) variability as measured by large standard deviation (AOR: 2.5; = 0.023) were significantly associated with overall poor mean FPG results. Female sex was also significantly associated with dyslipidemia (AOR: 1.9; = 0.049).

CONCLUSION

The study showed that achievements of combined diabetic goals are generally poor.

摘要

背景

本研究的目的是评估糖尿病患者的目标达成情况,并探索与之相关的变量。

方法

2015年12月至2016年4月,对188名在阿伊德转诊医院门诊糖尿病诊所就诊的2型糖尿病患者进行了一项横断面研究。使用空腹血糖值评估血糖控制情况,并用总胆固醇和甘油三酯评估血脂情况。进行双变量和多变量逻辑回归分析,以确定与血糖控制不佳、高血压和血脂异常相关的因素。

结果

糖尿病平均病程为6.5年。仅8.5%的参与者实现了血糖、血脂和血压的综合目标。实现综合目标的男性多于女性。单独来看,超过三分之二的患者血糖控制不佳(67%),超过一半的参与者血脂(58.5%)和血压(52.1%)控制不佳。相当一部分患者(68.1%)除高血糖外还患有其他合并症。在双变量和多变量分析中,糖尿病病程较长(调整后比值比:3.4;P = 0.013)以及用大标准差衡量的每月空腹血糖(FPG)显著波动(调整后比值比:2.5;P = 0.023)与总体FPG均值不佳显著相关。女性性别也与血脂异常显著相关(调整后比值比:1.9;P = 0.049)。

结论

该研究表明糖尿病综合目标的达成情况总体较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/471e/5804378/2e712ccaca81/IJCD2017-5713187.001.jpg

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