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埃塞俄比亚奥罗米亚州西谢瓦地区公立医院糖尿病患者的血糖控制不佳及其相关因素:一项基于机构的横断面研究。

Poor glycemic control and its associated factors among diabetes patients attending public hospitals in West Shewa Zone, Oromia, Ethiopia: An Institutional based cross-sectional study.

作者信息

Abdissa Daba, Hirpa Delessa

机构信息

Department of Biomedical Sciences, College of Medical Sciences, Institute of Health Sciences, Jimma University, Oromia, Ethiopia.

Department of Public Health, College of Health Science and Medicine, Ambo University, Oromia, Ethiopia.

出版信息

Metabol Open. 2021 Dec 11;13:100154. doi: 10.1016/j.metop.2021.100154. eCollection 2022 Mar.

DOI:10.1016/j.metop.2021.100154
PMID:34977524
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8683587/
Abstract

PURPOSE

Diabetes mellitus (DM) is increasing at an alarming rate throughout the world and its complications of has become a major public health concern in all countries. Glycemic control is the most important predictor for DM related complications and deaths. However information on glycemic control remains scarce in Ethiopia including our study area. Hence, the aim of this study was to assess the magnitude and factors associated with poor glycemic control among diabetic outpatients at West Shewa public Hospitals, Ethiopia.

METHODS

A facility-based cross-sectional study was conducted from June 01 to September 30, 2020. Poor glycemic control was assessed by glycated hemoglobin level and a systematic random sampling method was employed to select participants. An interviewer-administered structured questionnaire was used and the data entered into Epi data version 3.1 and exported into SPSS version 22 for analysis. Logistic regression was conducted to identify predictors of poor glycemic control. A p-value of <0.05 was considered statistically significant.

RESULTS

A total of 390 participants were involved in the study with mean age of 46.45 (±15.6) years. The study finding showed that the prevalence of poor glycemic control was found to be 63.8%. Age of ≥50 years (AOR = 2.77; 95% CI: 0.15,0.85), being single (AOR = 2.55; 95% CI: 0.179,.857), having high low-density lipoprotein cholesterol (AOR = 3.44; 95% CI: 1.65, 7.12), being female gender (AOR = 2.4; 95%CI: 0.31,0.816), alcohol intake (AOR = 1.88; 95% CI: 1.135, 3.1) and presence of diabetic peripheral neuropathy (AOR = 1.24; 1.1,1.39) were associated with poor glycemic control.

CONCLUSION

About two-thirds of participants had poor blood glucose control. Increased age, high low-density lipoprotein cholesterol, family history of diabetes, being single, being female, diabetic peripheral neuropathy and alcohol intake were associated with poor glycemic control. Hence, effort should be made towards reducing these factors among DM patients by the concerned body.

摘要

目的

糖尿病在全球正以惊人的速度增长,其并发症已成为所有国家主要的公共卫生问题。血糖控制是糖尿病相关并发症和死亡的最重要预测因素。然而,在埃塞俄比亚,包括我们的研究区域,关于血糖控制的信息仍然匮乏。因此,本研究的目的是评估埃塞俄比亚西谢瓦公立医院糖尿病门诊患者中血糖控制不佳的程度及其相关因素。

方法

于2020年6月1日至9月30日进行了一项基于机构的横断面研究。通过糖化血红蛋白水平评估血糖控制不佳情况,并采用系统随机抽样方法选择参与者。使用访谈员管理的结构化问卷,数据录入Epi data 3.1版本,并导出到SPSS 22版本进行分析。进行逻辑回归以确定血糖控制不佳的预测因素。p值<0.05被认为具有统计学意义。

结果

共有390名参与者参与研究,平均年龄为46.45(±15.6)岁。研究结果显示,血糖控制不佳的患病率为63.8%。年龄≥50岁(比值比=2.77;95%置信区间:0.15,0.85)、单身(比值比=2.55;95%置信区间:0.179,0.857)、低密度脂蛋白胆固醇水平高(比值比=3.44;95%置信区间:1.65,7.12)、女性(比值比=2.4;95%置信区间:0.31,0.816)、饮酒(比值比=1.88;95%置信区间:1.135,3.1)以及存在糖尿病周围神经病变(比值比=1.24;1.1,1.39)与血糖控制不佳相关。

结论

约三分之二的参与者血糖控制不佳。年龄增加、低密度脂蛋白胆固醇水平高、糖尿病家族史、单身、女性、糖尿病周围神经病变和饮酒与血糖控制不佳相关。因此,相关机构应努力减少糖尿病患者中的这些因素。

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