Sharma Pooja, Kumar Manoj, Bhalla Vandana
Department of Chemistry, UGC Sponsored Centre of Advanced Studies-II, Guru Nanak Dev University, Amritsar 143005, Punjab, India.
ACS Omega. 2020 Jul 31;5(31):19654-19660. doi: 10.1021/acsomega.0c02315. eCollection 2020 Aug 11.
The "metal-free", easy-to-prepare fluorescent supramolecular assemblies based on anthracene/perylene bisamide (PBI) derivatives have been developed for the distinct detection of organophosphate (CPF) and organochlorine (DCN) pesticides in aqueous media. The supramolecular assemblies of anthracene derivative show rapid and highly selective "on-on" response toward organophosphate (CPF), which is attributed to the formation of CPF-induced formation of "closely packed" assemblies. A detection limit in the nanomolar range is observed for CPF. On the other hand, the inner filter effect is proposed as the mechanism for the "on-off" detection of DCN using supramolecular assemblies of the anthracene derivative. This is the first report on the development of fluorescent materials having the potential to differentiate between organophosphate and organochlorine pesticides. The assemblies of anthracene derivative also act as "enzyme mimic" as organophosphate pesticide show a preferential affinity for assemblies of derivative over acetylcholinesterase enzyme. Further, the real-time applications of supramolecular assemblies have also been explored for the detection of CPF and DCN in spiked water and in agricultural products such as grapes and apples.
基于蒽/苝双酰胺（PBI）衍生物的“无金属”、易于制备的荧光超分子组装体已被开发用于在水性介质中特异性检测有机磷酸酯（毒死蜱，CPF）和有机氯（狄氏剂，DCN）农药。蒽衍生物的超分子组装体对有机磷酸酯（CPF）表现出快速且高度选择性的“开启-开启”响应，这归因于CPF诱导形成“紧密堆积”的组装体。对CPF观察到纳摩尔范围内的检测限。另一方面，提出内滤效应是使用蒽衍生物超分子组装体对DCN进行“开启-关闭”检测的机制。这是关于开发具有区分有机磷酸酯和有机氯农药潜力的荧光材料的首次报道。蒽衍生物的组装体还充当“酶模拟物”，因为有机磷酸酯农药对衍生物的组装体表现出比对乙酰胆碱酯酶更高的亲和力。此外，还探索了超分子组装体在加标水以及葡萄和苹果等农产品中检测CPF和DCN的实时应用。
