Department of Prosthodontics, Affiliated Stomatological Hospital of Nanchang University, Nanchang 330006, China.
The Key Laboratory of Oral Biomedicine, Jiangxi Province, Nanchang 330006, China.
Curr Pharm Des. 2018;24(8):926-935. doi: 10.2174/1381612824666180219125655.
Construction of antibacterial surfaces or films is of great interest in various fields including biomedicine, food, agriculture and so on. So far, a number of antibacterial agents have been used to construct antibacterial surfaces. Layer-by-Layer (LbL) assembly is a simple and versatile deposition process for fabricating multilayer thin films with great advantages to control the architecture and composition of the films. In this review, we give a brief introduction of LbL, and different materials used to fabricate antibacterial surfaces with LbL assembly approach are described as well as their drawbacks. Much attention is also paid to the recent development of multifunctional and intelligent antibacterial surfaces. Moreover, the advantages and limitations of these different types of antibacterial materials are summarized and subsequently directions for future development are proposed.
构建抗菌表面或薄膜在包括生物医药、食品、农业等多个领域都具有重要意义。迄今为止，已经有许多抗菌剂被用于构建抗菌表面。层层自组装（LbL）是一种简单且多功能的沉积工艺，可用于制造具有极大优势的多层薄膜，以控制薄膜的结构和组成。在本综述中，我们简要介绍了 LbL，并描述了使用 LbL 组装方法制造抗菌表面的不同材料及其缺点。我们还特别关注多功能和智能抗菌表面的最新发展。此外，总结了这些不同类型抗菌材料的优缺点，并提出了未来发展的方向。
