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乳头状甲状腺癌幸存者的妊娠情况。

Pregnancy in papillary thyroid cancer survivors.

作者信息

Beksaç Kemal, Aktoz Fatih, Örgül Gökçen, Çelik Hasan Tolga, Özgü-Erdinç A Seval, Beksaç M Sinan

机构信息

Clinic of General Surgery, University of Health Sciences, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey

Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe University School of Medicine, Ankara, Turkey

出版信息

J Turk Ger Gynecol Assoc. 2018 Jun 4;19(2):94-97. doi: 10.4274/jtgga.2017.0057. Epub 2018 Feb 20.

DOI:10.4274/jtgga.2017.0057
PMID:29469032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5994817/
Abstract

OBJECTIVE

To evaluate “papillary thyroid carcinoma-pregnancy” interaction among cancer survivors.

MATERIAL AND METHODS

The clinical records of 8 pregnant women who received treatment for papillary thyroid cancer before their pregnancy were evaluated. Clinical features, pregnancy/perinatal outcomes and high-risk factors were compared with 45 controls who were randomly assigned from the institutional perinatal medicine database.

RESULTS

Patients in the cancer group were older than the control group (34.3 vs 29.8 years). The cesarean section rate was higher (62.5% vs 33.3%) and the APGAR scores at the 1 and 5 minutes were lower in the cancer group.

CONCLUSION

Management of pregnancies with papillary thyroid cancer treatment and follow-up requires a multidisciplinary approach with careful antenatal care and perinatal surveillance. Patients who have received papillary thyroid cancer treatment can safely undergo pregnancy.

摘要

目的

评估癌症幸存者中“甲状腺乳头状癌-妊娠”的相互作用。

材料与方法

对8例在妊娠前接受过甲状腺乳头状癌治疗的孕妇的临床记录进行评估。将临床特征、妊娠/围产期结局及高危因素与从机构围产医学数据库中随机选取的45例对照进行比较。

结果

癌症组患者年龄大于对照组(34.3岁对29.8岁)。癌症组剖宫产率更高(62.5%对33.3%),且1分钟和5分钟时的阿氏评分更低。

结论

甲状腺乳头状癌治疗及随访的妊娠管理需要多学科方法,包括仔细的产前护理和围产期监测。接受过甲状腺乳头状癌治疗的患者可以安全妊娠。

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Retrospective evaluation of pregnant women with celiac disease.对患有乳糜泻的孕妇进行回顾性评估。
J Turk Ger Gynecol Assoc. 2017 Mar 15;18(1):56-59. doi: 10.4274/jtgga.2016.0198.
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Advanced thyroid carcinoma in pregnancy: case report of two pregnancies.妊娠期晚期甲状腺癌:两例妊娠病例报告
Gynecol Endocrinol. 2015;31(11):852-5. doi: 10.3109/09513590.2015.1018165. Epub 2015 Sep 29.
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Placental Angiogenic Factors Are Associated With Maternal Thyroid Function and Modify hCG-Mediated FT4 Stimulation.胎盘血管生成因子与母体甲状腺功能相关,并可调节 hCG 介导的 FT4 刺激。
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Risk of congenital anomalies associated with antithyroid treatment during pregnancy: a meta-analysis.孕期抗甲状腺治疗与先天性异常的风险:一项荟萃分析。
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Psychosocial distress in patients with thyroid cancer.甲状腺癌患者的心理社会困扰
Otolaryngol Head Neck Surg. 2015 Apr;152(4):644-9. doi: 10.1177/0194599814565761. Epub 2015 Jan 8.
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Cancer statistics, 2015.癌症统计数据,2015 年。
CA Cancer J Clin. 2015 Jan-Feb;65(1):5-29. doi: 10.3322/caac.21254. Epub 2015 Jan 5.
8
Cancer-related worry in Canadian thyroid cancer survivors.加拿大甲状腺癌幸存者与癌症相关的担忧。
J Clin Endocrinol Metab. 2015 Mar;100(3):977-85. doi: 10.1210/jc.2014-3169. Epub 2014 Nov 13.
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Menstrual and reproductive factors in the risk of differentiated thyroid carcinoma in young women in France: a population-based case-control study.法国年轻女性中分化型甲状腺癌发病风险与月经和生殖因素的关系:一项基于人群的病例对照研究。
Am J Epidemiol. 2014 Nov 15;180(10):1007-17. doi: 10.1093/aje/kwu220. Epub 2014 Sep 30.
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Discrepant serum and urine β-hCG results due to production of β-hCG by a cribriform-morular variant of thyroid papillary carcinoma.甲状腺乳头状癌筛状-桑葚状变体产生β-hCG导致血清和尿液β-hCG结果出现差异。
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