Sharma D, Singh G
Department of Radiotherapy, VMMC and Safdarjung Hospital, New Delhi, India.
Indian J Cancer. 2017 Apr-Jun;54(2):397-400. doi: 10.4103/ijc.IJC_225_17.
This retrospective observational study was done to analyze age, gender, site of primary tumor and histological characterstics in patients of colorectal carcinoma in the first two decades of life.
A total of 373 patients of colorectal patients were registered in the Department of Radiation Oncology from January 2010 to December 2015. Patients who were <20 years of age were analyzed for clinicopathological characteristic.
In our study, a total of 29 out of 373 patients (7.75%) were ≤20 years. Male to female distribution was 2.2:1. Younger age group presented with advanced Stage III and IV 58.62% and 10.34% patients, respectively. Only 9 (30.5%) patients were of Stage I and II. The most common involved site was rectum in 21 (72.41%) patients, followed by rectosigmoid involvement in 5 (17.24%).
Colorectal carcinoma in young adults is usually locally advanced or metastatic. Therefore, the diagnosis of CRC should be done at early and curable stage. Bleeding per rectum in a younger age group should not be ignored but must be properly evaluated.
本回顾性观察研究旨在分析20岁前结直肠癌患者的年龄、性别、原发肿瘤部位及组织学特征。
2010年1月至2015年12月期间，放射肿瘤学系共登记了373例结直肠癌患者。对年龄小于20岁的患者进行临床病理特征分析。
在我们的研究中，373例患者中有29例（7.75%）年龄≤20岁。男女比例为2.2:1。较年轻年龄组中分别有58.62%和10.34%的患者表现为III期和IV期晚期。只有9例（30.5%）患者为I期和II期。最常见的受累部位是直肠，有21例（72.41%）患者，其次是直肠乙状结肠受累，有5例（17.24%）。
年轻成年人的结直肠癌通常为局部晚期或转移性。因此，应在早期可治愈阶段进行结直肠癌的诊断。较年轻年龄组的直肠出血不应被忽视，而必须进行适当评估。
