Xue-Hui Shen, Jian-Rong Dai, Le-Ping Sun, Zhong-Yu Fu, Ye-Fang Li, Guo-Li Qu, Wei Wang, Yun-Tian Xing, Yi-An Wang, You-Sheng Liang
Dantu District Center for Disease Control and Prevention, Zhenjiang City, Jiangsu Province, Zhenjiang 212004, China.
Jiangsu Institute of Parasitic Diseases, Key Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasites and Vector Control Technology, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2016 Oct 18;28(5):502-506. doi: 10.16250/j.32.1374.2016170.
To describe the growth and development of in goat and the intensity and temporal distribution of eggs excreted by goat feces, so as to provide baseline data for the control and elimination of the role of goat in the transmission of schistosomiasis.
The goat animal models of schistosomiasis were established, and stool samples were collected for parasitological examinations. The number of adult worms recovered, variation of schistosomes in goat at different time points post-infection, number of eggs in schistosomes, variation in number and temporal profiles of eggs excreted from goat feces were observed.
Of the 6 schistosome-infected goat, 415 adult worms were recovered, with a mean adult worm recovery of 34.58% (range, 23.00% to 45.50%). Among the 5 goat infected with 200 cercariae each, 47, 93, 77, 74 and 73 adult worms were recovered 2, 5, 8, 11 and 14 months post-infection, respectively. There were (200.00±42.33), (226.20±45.88), (168.20±25.85), (183.80±55.13) and (190.80±53.53) eggs detected in female schistosomes. The mean prepatent period of eggs excreted by 10 infected goat was (37.7±3.02) d. From 2 to 14 months post-infection, 7 batches of goat feces were hatched, and there were 30, 23, 14, 1 and 2 times for miracidium intensity of "++++", "+++", "++", "+" and "-", respectively, with 42.86%, 32.86%, 20.00%, 1.43% and 2.86% constituent ratios of miracidium intensity.
Approximately 1/3 cercariae may develop to adults in goats post-infection, and the prepatent period of eggs is (37.7±3.02) d. There is no remarkable decrease seen in the number of adult worms, eggs in female schistosomes and eggs in goat feces within 14 months post-infection. Our findings suggest a long duration for infected goat in the transmission of schistosomiasis, and there is no evidence to prove the "self-cure" phenomenon in goat, indicating that goat is an important source of infection for schistosomiasis japonica.
描述山羊体内血吸虫的生长发育情况以及山羊粪便中排出虫卵的强度和时间分布，为控制和消除山羊在血吸虫病传播中的作用提供基线数据。
建立山羊血吸虫病动物模型，采集粪便样本进行寄生虫学检查。观察回收的成虫数量、感染后不同时间点山羊体内血吸虫的变化、血吸虫体内的虫卵数量、山羊粪便中排出虫卵数量的变化及其时间分布情况。
在6只感染血吸虫的山羊中，回收成虫415条，成虫平均回收率为34.58%（范围为23.00%至45.50%）。在5只每只感染200条尾蚴的山羊中，感染后2、5、8、11和14个月分别回收成虫47、93、77、74和73条。在雌虫体内检测到的虫卵数量分别为（200.00±42.33）、（226.20±45.88）、（168.20±25.85）、（183.80±55.13）和（190.80±53.53）个。10只感染山羊排出虫卵的平均潜伏期为（37.7±3.02）天。感染后2至14个月，对7批次山羊粪便进行孵化，“++++”、“+++”、“++”、“+”和“-”毛蚴强度分别出现30、23、14、1和2次，其构成比分别为42.86%、32.86%、20.00%、1.43%和2.86%。
感染后约1/3的尾蚴在山羊体内可发育为成虫，虫卵潜伏期为（37.7±3.02）天。感染后14个月内，成虫数量、雌虫体内虫卵数量及山羊粪便中虫卵数量均未见明显下降。我们的研究结果表明，感染山羊在血吸虫病传播中持续时间较长，且没有证据证明山羊存在“自愈”现象，这表明山羊是日本血吸虫的重要传染源。
