在随访厚脉络膜色素上皮病变患者时，发现一例中心性浆液性脉络膜视网膜病变患者脉络膜厚度发生变化。
CHOROIDAL THICKNESS CHANGES IN A PATIENT DIAGNOSED WITH CENTRAL SEROUS CHORIORETINOPATHY DURING FOLLOW-UP FOR PACHYCHOROID PIGMENT EPITHELIOPATHY.
机构信息
Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan; and.
Kaimeido Eye and Dental Clinic, Sapporo, Japan.
出版信息
Retin Cases Brief Rep. 2021 Jan 1;15(1):10-14. doi: 10.1097/ICB.0000000000000728.
PURPOSE
To evaluate chronological changes in choroidal thickness in a patient with pachychoroid pigment epitheliopathy (PPE) who was later diagnosed with central serous chorioretinopathy (CSC) during follow-up.
METHODS
Case report.
RESULTS
A 43-year-old man complained of metamorphopsia in the left eye. Funduscopy showed several punctate white subretinal lesions at the macula, but no macular serous retinal detachment in the left eye. Retinal pigment epithelium abnormality without serous retinal detachment at the macula on optical coherence tomography and choroidal vascular hyperpermeability on indocyanine green angiography suggested PPE in the left eye. Macular lesions disappeared with no treatment. Twenty-five months after the initial visit, PPE recurred in the left eye. Thirty-five months after the initial visit, the patient was diagnosed with CSC in the left eye. Macular serous retinal detachment spontaneously resolved. In the eye with PPE and CSC, the choroid was consistently thicker than that in the fellow eye during follow-up. The choroid became thicker during the alternate onsets of PPE and CSC and thinner after regression of these diseases.
CONCLUSION
These results suggest that PPE and CSC overlap clinically and choroidal thickening is involved in the pathogenesis of both diseases.
目的
评估 1 例后来被诊断为中心性浆液性脉络膜视网膜病变（CSC）的肥厚性脉络膜色素上皮病变（PPE）患者脉络膜厚度的随时间变化。
方法
病例报告。
结果
1 名 43 岁男性左眼出现视物变形。眼底检查显示黄斑区有几个点状白色视网膜下病变，但左眼无黄斑浆液性视网膜脱离。左眼光学相干断层扫描显示视网膜色素上皮异常，无黄斑区浆液性视网膜脱离，吲哚青绿血管造影显示脉络膜血管通透性增加，提示左眼 PPE。黄斑病变未经治疗自行消退。初次就诊后 25 个月，左眼 PPE 再次发作。初次就诊后 35 个月，左眼被诊断为 CSC。黄斑区浆液性视网膜脱离自发消退。在 PPE 和 CSC 的眼中，脉络膜在随访期间始终比对侧眼厚。在 PPE 和 CSC 的交替发作期间，脉络膜变厚，在这些疾病消退后变薄。
结论
这些结果表明 PPE 和 CSC 在临床上有重叠，脉络膜增厚与这两种疾病的发病机制有关。
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