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面向基于科学证据的肿瘤治疗个体口腔护理的卫生专业人员指南。

Guide for health professionals addressing oral care for individuals in oncological treatment based on scientific evidence.

机构信息

Curso de Odontologia, Universidade Ceuma, Rua Josué Montello, No. 1, Renascença II, São Luís, Maranhão, 65075-120, Brazil.

Instituto Maranhense de Oncologia Aldenora Bello, São Luís, Rua Seroa da Mota, No. 23, Apeadouro, São Luís, Maranhão, 65031-630, Brazil.

出版信息

Support Care Cancer. 2018 Aug;26(8):2651-2661. doi: 10.1007/s00520-018-4111-7. Epub 2018 Feb 22.

Abstract

OBJECTIVE

Oncological treatment can cause changes in the oral cavity compromising oral functions. The aim of the study was, based on a systematic review, to draft a guide directed at the team of health professionals involved in the oral care of oncological patients.

METHODS

A systematic search of the literature was performed for articles published between 2000 and April 2017. Searches were made of electronic databases and hand search. The inclusion criteria were systematic reviews of randomized clinical trials (RCTs) and RCTs published in English, involving pediatric and adult oncological patients and focused on the prevention and treatment of oral complications as well as studies addressing the maintenance of oral health. Among the 1237 studies identified, 129 were pre-selected and 54 were selected to form the basis for the clinical guide.

RESULTS

The studies analyzed stress the need for oral assessments as well as preventive and curative actions prior to oncological treatment. To minimize the severity of oral problems, the studies emphasize daily oral care, the treatment of xerostomia with saliva substitute and hydration, and low-level laser therapy, nystatin, acyclovir, respectively, for the prevention and treatment of oral mucositis, oral candidiasis, and infection by herpes simplex virus. Thus, the guide produced addresses oral assessments and professional and home care before, during, and after oncological treatment.

CONCLUSION

The guide drafted has the function of assisting health professionals involved in the oral care of patients with cancer, enabling the prevention or treatment of oral complications stemming from oncological treatment.

摘要

目的

肿瘤治疗可引起口腔功能改变。本研究旨在通过系统评价,为参与口腔癌患者口腔护理的医疗团队制定一份指南。

方法

对 2000 年至 2017 年 4 月期间发表的文章进行了系统的文献检索。检索了电子数据库和手工检索。纳入标准为针对儿童和成人肿瘤患者的预防和治疗口腔并发症的系统评价和随机对照试验(RCT),以及关注口腔健康维护的研究。在确定的 1237 项研究中,预筛选了 129 项,选择了 54 项作为临床指南的基础。

结果

分析的研究强调了在进行肿瘤治疗前进行口腔评估以及预防和治疗的必要性。为了最大限度地减少口腔问题的严重程度,研究强调了日常口腔护理、使用唾液替代物和水合作用治疗口干、以及低水平激光治疗、制霉菌素、阿昔洛韦,分别用于预防和治疗口腔黏膜炎、口腔念珠菌病和单纯疱疹病毒感染。因此,制定的指南涉及口腔评估以及肿瘤治疗前、中、后的专业和家庭护理。

结论

本指南的制定有助于参与癌症患者口腔护理的医疗专业人员,预防或治疗源于肿瘤治疗的口腔并发症。

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