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Estimates of the prevalence of and current treatment practices for rheumatoid arthritis in Japan using reimbursement data from health insurance societies and the IORRA cohort (I).利用医疗保险协会和 IORRA 队列（I）的报销数据估计日本类风湿关节炎的患病率和当前治疗实践。
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Major depressive disorder in patients with rheumatoid arthritis.类风湿关节炎患者中的重度抑郁症。
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日本类风湿性关节炎患者抑郁症的成本：来自行政数据的证据。

Cost of Depression in Japanese Patients with Rheumatoid Arthritis: Evidence from Administrative Data.

作者信息

Guelfucci Florent, Kaneko Yuko, Mahlich Jörg, Sruamsiri Rosarin

机构信息

Creativ-Ceutical, Paris, France.

Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

出版信息

Rheumatol Ther. 2018 Jun;5(1):171-183. doi: 10.1007/s40744-018-0096-4. Epub 2018 Feb 22.

DOI:10.1007/s40744-018-0096-4
PMID:29470833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5935627/
Abstract

INTRODUCTION

To determine the cost of depression comorbidity among Japanese adults with rheumatoid arthritis (RA).

METHODS

A retrospective database study of 8968 patients diagnosed with RA between 2010 and 2015 and treated with any RA medication was conducted. Health care utilization characteristics were compared between patients with and without a comorbidity of depression. Propensity score matching was applied to ensure a balanced comparison between the two cohorts.

RESULTS

The prevalence of a depression comorbidity was found for 5% of the total RA patients. This comorbidity was associated with 62% (56%) higher total outpatient visits and 66% (163%) higher rate of emergency room visits after 6 (12) months.

CONCLUSIONS

Burden of depression among RA patients in Japan is relatively high and awareness for depression as a comorbidity of RA needs to be reinforced.

FUNDING

Janssen Pharmaceutical KK.

摘要

引言

确定日本成年类风湿关节炎（RA）患者中抑郁症合并症的成本。

方法

对2010年至2015年间诊断为RA并接受任何RA药物治疗的8968例患者进行回顾性数据库研究。比较了有和没有抑郁症合并症的患者的医疗保健利用特征。应用倾向得分匹配以确保两个队列之间的平衡比较。

结果

在所有RA患者中，抑郁症合并症的患病率为5%。这种合并症与6个月（12个月）后门诊总就诊次数增加62%（56%）以及急诊就诊率增加66%（163%）相关。

结论

日本RA患者中抑郁症负担相对较高，需要加强对抑郁症作为RA合并症的认识。

资金来源

杨森制药株式会社。