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用于光学相干断层扫描的102纳米、44.5兆赫兹无惯性扫频光源,采用锁模光纤激光器和时间拉伸技术

102-nm, 44.5-MHz inertial-free swept source by mode-locked fiber laser and time stretch technique for optical coherence tomography.

作者信息

Kang Jiqiang, Feng Pingping, Wei Xiaoming, Lam Edmund Y, Tsia Kevin K, Wong Kenneth K Y

出版信息

Opt Express. 2018 Feb 19;26(4):4370-4381. doi: 10.1364/OE.26.004370.

Abstract

A swept source with both high repetition-rate and broad bandwidth is indispensable to enable optical coherence tomography (OCT) with high imaging rate and high axial resolution. However, available swept sources are commonly either limited in speed (sub-MHz) by inertial or kinetic component, or limited in bandwidth (<100 nm) by the gain medium. Here we report an ultrafast broadband (over 100 nm centered at 1.55-µm) all-fiber inertial-free swept source built upon a high-power dispersion-managed fiber laser in conjunction with an optical time-stretch module which bypasses complex optical amplification scheme, which result in a portable and compact implementation of time-stretch OCT (TS-OCT) at A-scan rate of 44.5-MHz, axial resolution of 14 µm in air (or 10 µm in tissue), and flat sensitivity roll-off within 4.3 mm imaging range. Together with the demonstration of two- and three-dimensional OCT imaging of a mud-fish eye anterior segment, we also perform comprehensive studies on the imaging depth, receiver bandwidth, and group velocity dispersion condition. This all-fiber inertia-free swept source could provide a promising source solution for SS-OCT system to realize high-performance volumetric OCT imaging in real time.

摘要

具有高重复率和宽带宽的扫频光源对于实现高成像速率和高轴向分辨率的光学相干断层扫描(OCT)至关重要。然而,现有的扫频光源通常要么受到惯性或动力学组件的限制而在速度上较慢(亚兆赫兹),要么受到增益介质的限制而带宽较窄(<100 nm)。在此,我们报告了一种基于高功率色散管理光纤激光器并结合光学时间拉伸模块构建的超快宽带(中心波长为1.55 µm时超过100 nm)全光纤无惯性扫频光源,该模块绕过了复杂的光放大方案,从而实现了便携式、紧凑的时间拉伸OCT(TS-OCT),其A扫描速率为44.5 MHz,空气中轴向分辨率为14 µm(组织中为10 µm),在4.3 mm成像范围内灵敏度呈平坦下降。在展示了弹涂鱼眼前节的二维和三维OCT成像的同时,我们还对成像深度、接收器带宽和群速度色散条件进行了全面研究。这种全光纤无惯性扫频光源可为SS-OCT系统提供一个有前景的光源解决方案,以实现高性能的实时体层OCT成像。

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