己糖1,6 - 二磷酸酯和果糖2,6 - 二磷酸酯对从蜜蜂飞行肌中纯化的6 - 磷酸果糖激酶活性的拮抗作用。
Antagonistic effects of hexose 1,6-bisphosphates and fructose 2,6-bisphosphate on the activity of 6-phosphofructokinase purified from honey-bee flight muscle.
作者信息
Wegener G, Schmidt H, Leech A R, Newsholme E A
出版信息
Biochem J. 1986 Jun 15;236(3):925-8. doi: 10.1042/bj2360925.
Abstract
6-Phosphofructokinase purified from honey-bee flight muscle is inhibited by ATP and, unusually, by glucose 1,6-bisphosphate and fructose 1,6-bisphosphate. The inhibition by either of the bisphosphates is not relieved by AMP, but is relieved by fructose 6-phosphate and especially by fructose 2,6-bisphosphate. Lack of effect by AMP is consistent with a low activity of adenylate kinase in this muscle.
摘要
从蜜蜂飞行肌中纯化得到的6-磷酸果糖激酶受到ATP的抑制，不同寻常的是，它还受到1,6-二磷酸葡萄糖和1,6-二磷酸果糖的抑制。这两种二磷酸化合物中的任何一种所引起的抑制作用都不会被AMP解除，但会被6-磷酸果糖，尤其是2,6-二磷酸果糖解除。AMP不起作用这一点与该肌肉中腺苷酸激酶的低活性是一致的。
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Antagonistic effects of hexose 1,6-bisphosphates and fructose 2,6-bisphosphate on the activity of 6-phosphofructokinase purified from honey-bee flight muscle.己糖1,6 - 二磷酸酯和果糖2,6 - 二磷酸酯对从蜜蜂飞行肌中纯化的6 - 磷酸果糖激酶活性的拮抗作用。
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