Kilpatrick D, Webber S B
Cathet Cardiovasc Diagn. 1986;12(5):317-23. doi: 10.1002/ccd.1810120508.
The profiles of blood velocity within arterial stenoses have been measured using fiber optic laser Doppler anemometry (FOLDA). The arterial stenoses were created in arteries and tubes of similar size to human coronary arteries and were perfused in vitro at pressures and flows typical of those in the human circulation. At very low flow rates, flow and peak velocity are linearly related, and thus peak velocity measurement can predict internal cross-sectional areas accurately. With higher flow rates, the intravascular velocities are not linearly related to flow and cannot be used to measure internal cross-sectional area. This is due to flattening of the velocity profile at both more severe stenoses and higher flow rates.
已使用光纤激光多普勒血流仪（FOLDA）测量了动脉狭窄部位的血流速度剖面。在与人类冠状动脉大小相似的动脉和血管中制造动脉狭窄，并在体外以人体循环典型的压力和流量进行灌注。在非常低的流速下，流量与峰值速度呈线性相关，因此峰值速度测量可以准确预测内部横截面积。在较高流速下，血管内速度与流量不是线性相关的，不能用于测量内部横截面积。这是由于在更严重的狭窄和更高的流速下速度剖面变平所致。
