Department of Pharmacognosy and Environmental Medicines, University of Nigeria, Nsukka 410001, Nigeria.
Department of Pharmaceutical and Medicinal Chemistry, University of Nigeria, Nsukka 410001, Nigeria.
J Ethnopharmacol. 2018 May 23;218:1-15. doi: 10.1016/j.jep.2018.02.034.
Malaria is a serious public health problem especially in sub-Saharan African countries such as Nigeria. The causative parasite is increasingly developing resistance to the existing drugs. There is urgent need for alternative and affordable therapy from medicinal plants which have been used by the indigenous people for many years.
This study was conducted to document the medicinal plant species traditionally used by the people of Nsukka Local Government Area in south-eastern Nigeria for the treatment of malaria.
A total of 213 respondents, represented by women (59.2%) and men (40.8%), were interviewed using a semi-structured questionnaire. The results were analysed and discussed in the context of previously published information on anti-malarial and phytochemical studies of the identified plants.
The survey revealed that 50 plant species belonging to 30 botanical families were used in this region for the treatment of malaria. The most cited families were Apocynaceae (13.3%), Annonaceae (10.0%), Asteraceae (10.0%), Lamiaceae (10.0%), Poaceae (10.0%), Rubiaceae (10.0%) and Rutaceae (10.0%). The most cited plant species were Azadirachta indica (11.3%), Mangifera indica (9.1%), Carica papaya (8.5%), Cymbopogon citratus (8.5%) and Psidium guajava (8.5%).
The present findings showed that the people of Nsukka use a large variety of plants for the treatment of malaria. The identified plants are currently undergoing screening for anti-malarial, toxicity and chemical studies in our laboratory.
疟疾是一个严重的公共卫生问题,特别是在尼日利亚等撒哈拉以南的非洲国家。致病寄生虫对现有药物的耐药性日益增强。迫切需要从药用植物中寻找替代和负担得起的治疗方法,这些植物已被土著人民使用多年。
本研究旨在记录尼日利亚东南部Nsukka 地方政府区人民传统上用于治疗疟疾的药用植物物种。
共采访了 213 名受访者,其中女性(59.2%)和男性(40.8%)各占一半,采用半结构式问卷进行采访。结果根据以前发表的有关抗疟和鉴定植物的植物化学研究信息进行分析和讨论。
调查显示,该地区有 50 种植物属于 30 个科,用于治疗疟疾。被引用最多的科是夹竹桃科(13.3%)、番荔枝科(10.0%)、菊科(10.0%)、唇形科(10.0%)、禾本科(10.0%)、茜草科(10.0%)和芸香科(10.0%)。被引用最多的植物种是印楝(11.3%)、芒果(9.1%)、番木瓜(8.5%)、香茅草(8.5%)和番石榴(8.5%)。
本研究结果表明,Nsukka 地区的人们使用多种植物来治疗疟疾。目前,已确定的植物正在我们的实验室中进行抗疟、毒性和化学成分筛选。