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本文引用的文献

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Neurotransmitters and neuropeptides in gonadal steroid receptor-expressing cells in medial preoptic area subregions of the male mouse.雄性小鼠中内侧视前区亚区表达性腺类固醇受体的细胞中的神经递质和神经肽。
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Toward a Wiring Diagram Understanding of Appetite Control.迈向对食欲控制的线路图理解。
Neuron. 2017 Aug 16;95(4):757-778. doi: 10.1016/j.neuron.2017.06.014.
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The Strange Case of Aggression and the Brain.《攻击行为与大脑的奇异案例》
Neuron. 2017 Aug 16;95(4):734-737. doi: 10.1016/j.neuron.2017.07.041.
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Social Control of Hypothalamus-Mediated Male Aggression.下丘脑介导的雄性攻击行为的社会控制
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Biased Oxytocinergic Modulation of Midbrain Dopamine Systems.中脑多巴胺系统的偏倚性催产素能调节
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Identification of preoptic sleep neurons using retrograde labelling and gene profiling.利用逆行标记和基因谱分析鉴定视前区睡眠神经元
Nature. 2017 May 25;545(7655):477-481. doi: 10.1038/nature22350. Epub 2017 May 17.
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Sexual Dimorphism of Parental Care: From Genes to Behavior.双亲照料的性别二态性:从基因到行为。
Annu Rev Neurosci. 2017 Jul 25;40:273-305. doi: 10.1146/annurev-neuro-072116-031447. Epub 2017 Apr 24.
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The genetic basis of parental care evolution in monogamous mice.一夫一妻制小鼠中亲代抚育行为进化的遗传基础。
Nature. 2017 Apr 27;544(7651):434-439. doi: 10.1038/nature22074. Epub 2017 Apr 19.
9
Climate and the distribution of cooperative breeding in mammals.气候与哺乳动物合作繁殖的分布
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亲代行为的神经控制。

Neural control of parental behaviors.

机构信息

Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Center for Brain Science, Harvard University, Cambridge, MA, USA.

Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Center for Brain Science, Harvard University, Cambridge, MA, USA.

出版信息

Curr Opin Neurobiol. 2018 Apr;49:116-122. doi: 10.1016/j.conb.2018.02.002. Epub 2018 Feb 23.

DOI:10.1016/j.conb.2018.02.002
PMID:29482085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6029232/
Abstract

Parenting is a multicomponent social behavior that is essential for the survival of offspring in many species. Despite extensive characterization of individual brain areas involved in parental care, we do not fully understand how discrete aspects of this behavior are orchestrated at the neural circuit level. Recent progress in identifying genetically specified neuronal populations critical for parenting, and the use of genetic and viral tools for circuit-cracking now allow us to deconstruct the underlying circuitry and, thus, to elucidate how different aspects of parental care are controlled. Here we review the latest advances, outline possible organizational principles of parental circuits and discuss future challenges.

摘要

育儿是一种多成分的社会行为,对许多物种中后代的生存至关重要。尽管已经广泛描述了与亲代照料相关的个体脑区,但我们仍不完全理解这种行为的离散方面是如何在神经回路水平上协调的。最近在鉴定对亲代行为至关重要的遗传特化神经元群体方面取得的进展,以及使用遗传和病毒工具进行回路破解,现在使我们能够解构潜在的回路,从而阐明亲代照料的不同方面是如何受到控制的。在这里,我们回顾了最新的进展,概述了亲代回路的可能组织原则,并讨论了未来的挑战。