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One Step Surgery for Cutaneous Melanoma: "We Cannot Solve Our Problems with the Same Thinking We Used When We Created Them?".皮肤黑色素瘤的一步手术:“我们不能用创造问题时的相同思维来解决问题?”
Open Access Maced J Med Sci. 2017 Oct 10;5(6):774-776. doi: 10.3889/oamjms.2017.168. eCollection 2017 Oct 15.
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New Safety Margins for Melanoma Surgery: Nice Possibility for Drinking of "Just That Cup of Coffee"?黑色素瘤手术的新安全边界:喝“那杯咖啡”的美好可能?
Open Access Maced J Med Sci. 2017 Jun 11;5(3):352-358. doi: 10.3889/oamjms.2017.068. eCollection 2017 Jun 15.

在全球普遍全球化背景下的创新与创新方法或伪创新?是时候觉醒了!

Innovations and Innovative Approaches or Pseudo-Innovations in the Context of General Globalization? It's Time to Wake Up!

作者信息

Tchernev Georgi

机构信息

Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior (MVR-Sofia), General Skobelev 79, 1606 Sofia, Bulgaria.

Onkoderma - Policlinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606, Sofia, Bulgaria.

出版信息

Open Access Maced J Med Sci. 2017 Dec 24;6(1):1-5. doi: 10.3889/oamjms.2018.057. eCollection 2018 Jan 25.

DOI:10.3889/oamjms.2018.057
PMID:29483969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5816271/
Abstract

Globalisation, scientific and technical progress are the basis of numerous innovative therapies for oncologic and non-oncologic diseases. It is another matter how much and by whom they are desired, and whether they have to be applied. When and how often? Innovative approaches should go towards simplification, universal distribution and application while at the same time analysis between the potential initial investment and the achieved final result should be made. An illustrative example for this is the targeted therapy for melanoma with its low baseline criteria or basic rules for its surgical treatment. Another example could be the confocal microscopy in the context of dysplastic nevus syndrome. Therapies for various autoimmune diseases should also be considered critically. In the current OAMJMS issue, as well as in some of our other ideas and statements reported also in OAMJMS, we are trying to answer at least to a part of these dilemmas, to provoke a critical point of view and to ask some simple questions: "Should any innovation be considered as a face value? Which is potentially beneficial for our patients? How could we regulate the processes to minimise the need for expensive medications for certain diseases? And, of course, we are also turning to our own mistakes by visualising the results of them!

摘要

全球化、科技进步是众多肿瘤及非肿瘤疾病创新疗法的基础。然而,这些疗法的需求程度、由谁需求以及是否必须应用则是另一回事。何时应用以及应用频率如何?创新方法应朝着简化、广泛传播和应用的方向发展,同时应分析潜在的初始投资与最终取得的成果。黑色素瘤的靶向治疗及其较低的基线标准或手术治疗基本规则就是一个例证。发育异常痣综合征背景下的共聚焦显微镜检查也可作为一个例子。对于各种自身免疫性疾病的治疗也应进行批判性思考。在本期《奥匈医学杂志》以及我们在该杂志上报道的其他一些观点和声明中,我们试图至少回答这些困境中的一部分问题,引发批判性观点,并提出一些简单问题:“是否应将任何创新视为表面价值?哪些创新对我们的患者可能有益?我们如何规范流程以尽量减少某些疾病对昂贵药物的需求?当然,我们也通过审视自身错误的结果来反思!