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黏液样-圆形细胞脂肪肉瘤:放射治疗后的MRI表现及其与疗效的关系。

Myxoid-round cell liposarcoma: MRI appearance after radiation therapy and relationship to response.

作者信息

Rosenberg Michael, Groth John V, Taljanovic Mihra S, Mar Winnie A

机构信息

Department of Radiology, University of Illinois Hospital & Health Sciences System, 1740 West Taylor Street, Suite 2600, Chicago, IL 60612.

Department of Pathology, University of Illinois Hospital & Health Sciences System, Third Floor, 1740 W. Taylor St., Chicago, IL 60612.

出版信息

Radiol Case Rep. 2017 Aug 12;12(4):811-814. doi: 10.1016/j.radcr.2017.06.017. eCollection 2017 Dec.

DOI:10.1016/j.radcr.2017.06.017
PMID:29484077
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5823305/
Abstract

Liposarcomas are classified into 4 different subtypes, with the myxoid-round cell variant demonstrating increased morbidity and metastatic potential dependent on cell composition. Unique to sarcomas, the myxoid-round cell liposarcoma is remarkably sensitive to radiation therapy in the pretreatment setting, owing to the tumor morphology and vascular distribution. Herein we report a case of myxoid-round cell liposarcoma within the deep soft tissues of the thigh of an 81-year-old male with excellent neoadjuvant response to radiation. We briefly review treatment options.

摘要

脂肪肉瘤分为4种不同的亚型,其中黏液样-圆形细胞亚型的发病率和转移潜能增加,这取决于细胞组成。黏液样-圆形细胞脂肪肉瘤作为肉瘤所特有的类型,由于其肿瘤形态和血管分布,在预处理阶段对放射治疗非常敏感。在此,我们报告一例81岁男性大腿深部软组织黏液样-圆形细胞脂肪肉瘤病例,该病例对新辅助放疗反应良好。我们简要回顾一下治疗方案。

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本文引用的文献

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Liposarcoma: Multimodality Management and Future Targeted Therapies.脂肪肉瘤:多模态管理与未来靶向治疗
Surg Oncol Clin N Am. 2016 Oct;25(4):761-73. doi: 10.1016/j.soc.2016.05.007. Epub 2016 Jul 30.
2
Imaging in Soft Tissue Sarcomas: Current Updates.软组织肉瘤的影像学:当前进展
Surg Oncol Clin N Am. 2016 Oct;25(4):645-75. doi: 10.1016/j.soc.2016.05.002.
3
Metastatic patterns of myxoid/round cell liposarcoma: a review of a 25-year experience.黏液样/圆形细胞脂肪肉瘤的转移模式:25年经验回顾
Sarcoma. 2012;2012:345161. doi: 10.1155/2012/345161. Epub 2012 Apr 1.
4
Imaging of liposarcoma: classification, patterns of tumor recurrence, and response to treatment.脂肪肉瘤的影像学表现:分类、肿瘤复发模式及治疗反应。
AJR Am J Roentgenol. 2011 Jul;197(1):W37-43. doi: 10.2214/AJR.10.5824.
5
Effectiveness of radiotherapy in myxoid sarcomas is associated with a dense vascular pattern.放疗对黏液样肉瘤的有效性与密集的血管模式相关。
Int J Radiat Oncol Biol Phys. 2008 Dec 1;72(5):1480-7. doi: 10.1016/j.ijrobp.2008.03.008. Epub 2008 Apr 28.
6
From the archives of the AFIP: imaging of musculoskeletal liposarcoma with radiologic-pathologic correlation.源自武装部队病理研究所档案:肌肉骨骼脂肪肉瘤的影像学表现及其与病理的相关性
Radiographics. 2005 Sep-Oct;25(5):1371-95. doi: 10.1148/rg.255055106.
7
Prognostic significance of MRI findings in patients with myxoid-round cell liposarcoma.黏液样-圆细胞脂肪肉瘤患者MRI表现的预后意义
AJR Am J Roentgenol. 2004 Mar;182(3):725-31. doi: 10.2214/ajr.182.3.1820725.