Funder K S, Rasmussen L S, Siersma V, Lohse N, Hesselfeldt R, Pedersen F, Hendriksen O M, Steinmetz J
Department of Anaesthesia, Centre of Head and Orthopaedics 4231, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Acta Anaesthesiol Scand. 2018 Apr;62(4):568-578. doi: 10.1111/aas.13092. Epub 2018 Feb 27.
Implementation of the first Danish helicopter emergency medical service (HEMS) was associated with reduced time from first medical contact to treatment at a specialized centre for patients with suspected ST elevation myocardial infarction (STEMI). We aimed to investigate effects of HEMS on mortality and labour market affiliation in patients admitted for primary percutaneous coronary intervention (PCI).
In this prospective observational study, we included patients with suspected STEMI within the region covered by the HEMS from January 1, 2010, to April 30, 2013, transported by either HEMS or ground emergency medical services (GEMS) to the regional PCI centre. The primary outcome was 30-day mortality.
Among the 384 HEMS and 1220 GEMS patients, time from diagnostic ECG to PCI centre arrival was lower with HEMS (median 71 min vs. 78 min with GEMS; P = 0.004). Thirty-day mortality was 5.0% and 6.2%, respectively (adjusted OR = 0.82, 95% CI 0.44-1.51, P = 0.52. Involuntary early retirement rates were 0.62 (HEMS) and 0.94 (GEMS) per 100 PYR (adjusted IRR = 0.68, 0.15-3.23, P = 0.63). The proportion of patients on social transfer payments longer than half of the follow-up time was 22.1% (HEMS) vs. 21.2% (adjusted OR = 1.10, 0.64-1.90, P = 0.73).
In an observational study of patients with suspected STEMI in eastern Denmark, no significant beneficial effect of helicopter transport could be detected on mortality, premature labour market exit or work ability. Only a study with random allocation to one system vs. another, along with a large sample size, will allow determination of superiority of helicopter transport.
丹麦首个直升机紧急医疗服务(HEMS)的实施,与疑似ST段抬高型心肌梗死(STEMI)患者从首次医疗接触到在专科中心接受治疗的时间缩短相关。我们旨在研究HEMS对接受直接经皮冠状动脉介入治疗(PCI)患者的死亡率和劳动力市场归属的影响。
在这项前瞻性观察性研究中,我们纳入了2010年1月1日至2013年4月30日期间在HEMS覆盖区域内疑似STEMI的患者,这些患者由HEMS或地面紧急医疗服务(GEMS)转运至区域PCI中心。主要结局为30天死亡率。
在384例HEMS患者和1220例GEMS患者中,HEMS组从诊断性心电图到抵达PCI中心的时间更短(中位数71分钟,GEMS组为78分钟;P = 0.004)。30天死亡率分别为5.0%和6.2%(校正比值比 = 0.82,95%置信区间0.44 - 1.51,P = 0.52)。每100人年的非自愿提前退休率分别为0.62(HEMS)和0.94(GEMS)(校正发病率比值比 = 0.68,0.15 - 3.23,P = 0.63)。在随访时间超过一半的时间里接受社会转移支付的患者比例为22.1%(HEMS)对21.2%(校正比值比 = 1.10,0.64 - 1.90,P = 0.73)。
在丹麦东部对疑似STEMI患者的一项观察性研究中,未发现直升机转运在死亡率、过早退出劳动力市场或工作能力方面有显著的有益效果。只有一项将患者随机分配至一种系统或另一种系统且样本量较大的研究,才能确定直升机转运的优越性。