Gunnarsson Sverrir I, Mitchell Joseph, Busch Mary S, Larson Brenda, Gharacholou S Michael, Li Zhanhai, Raval Amish N
Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin, Madison, WI.
Mayo Clinic Health System-Franciscan Healthcare, La Crosse, WI.
J Am Heart Assoc. 2017 Feb 2;6(2):e004936. doi: 10.1161/JAHA.116.004936.
The effect of physician-staffed helicopter emergency medical service (HEMS) on ST-elevation myocardial infarction (STEMI) patient transfer is unknown. The purpose of this study was to evaluate the characteristics and outcomes of physician-staffed HEMS (Physician-HEMS) versus non-physician-staffed (Standard-HEMS) in patients with STEMI.
We studied 398 STEMI patients transferred by either Physician-HEMS (n=327) or Standard-HEMS (n=71) for primary or rescue percutaneous coronary intervention at 2 hospitals between 2006 and 2014. Data were collected from electronic medical records and each institution's contribution to the National Cardiovascular Data Registry. Baseline characteristics were similar between groups. Median electrocardiogram-to-balloon time was longer for the Standard-HEMS group than for the Physician-HEMS group (118 vs 107 minutes; P=0.002). The Standard-HEMS group was more likely than the Physician-HEMS group to receive nitroglycerin (37% vs 15%; P<0.001) and opioid analgesics (42.3% vs 21.7%; P<0.001) during transport. In-hospital adverse outcomes, including cardiac arrest, cardiogenic shock, and serious arrhythmias, were more common in the Standard-HEMS group (25.4% vs 11.3%; P=0.002). After adjusting for age, sex, Killip class, and transport time, patients transferred by Standard-HEMS had increased risk of any serious in-hospital adverse event (odds ratio=2.91; 95% CI=1.39-6.06; P=0.004). In-hospital mortality was not statistically different between the 2 groups (9.9% in the Standard-HEMS group vs 4.9% in the Physician-HEMS group; P=0.104).
Patients with STEMI transported by Standard-HEMS had longer transport times, higher rates of nitroglycerin and opioid administration, and higher rates of adjusted in-hospital events. Efforts to better understand optimal transport strategies in STEMI patients are needed.
由医生配备的直升机紧急医疗服务(HEMS)对ST段抬高型心肌梗死(STEMI)患者转运的影响尚不清楚。本研究的目的是评估配备医生的HEMS(医生-HEMS)与未配备医生的HEMS(标准-HEMS)在STEMI患者中的特征和结局。
我们研究了2006年至2014年间在两家医院通过医生-HEMS(n = 327)或标准-HEMS(n = 71)转运以进行初次或抢救性经皮冠状动脉介入治疗的398例STEMI患者。数据从电子病历和各机构对国家心血管数据注册中心的贡献中收集。两组之间的基线特征相似。标准-HEMS组的心电图至球囊时间中位数比医生-HEMS组长(118对107分钟;P = 0.002)。标准-HEMS组在转运过程中比医生-HEMS组更有可能接受硝酸甘油(37%对15%;P < 0.001)和阿片类镇痛药(42.3%对21.7%;P < 0.001)。包括心脏骤停、心源性休克和严重心律失常在内的院内不良结局在标准-HEMS组中更常见(25.4%对11.3%;P = 0.002)。在调整年龄、性别、Killip分级和转运时间后,由标准-HEMS转运的患者发生任何严重院内不良事件的风险增加(比值比 = 2.91;95%可信区间 = 1.39 - 6.06;P = 0.004)。两组之间的院内死亡率无统计学差异(标准-HEMS组为9.9%,医生-HEMS组为4.9%;P = 0.104)。
由标准-HEMS转运的STEMI患者转运时间更长,硝酸甘油和阿片类药物使用率更高,调整后的院内事件发生率更高。需要努力更好地了解STEMI患者的最佳转运策略。