Department of Ophthalmology, Edith Wolfson Medical Center, Holon, Israel.
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Acta Ophthalmol. 2018 Aug;96(5):e592-e595. doi: 10.1111/aos.13722. Epub 2018 Feb 28.
To investigate the effects of bariatric surgery on intraocular pressure (IOP).
We prospectively enroled consecutive obese patients who underwent a laparoscopic sleeve gastrectomy procedure. We measured IOP prior to and 3-6 months following surgery and recorded medical and demographical parameters.
Thirty-two patients completed all evaluations. Mean age was 40.5 ± 12 and 24 (75%) were men. Following surgery, mean body-mass index (BMI) decreased from 42 ± 6 to 31 ± 8 (p < 0.001). The mean IOP decreased from 16.9 ± 4 mmHg to 14.1 ± 3 mmHg (p < 0.001). The extent of IOP reduction was correlated with the baseline IOP (Pearson r = 0.737, p < 0.001) and central corneal thickness (Pearson r = 0.453, p = 0.010).
In a cohort of obese individuals undergoing sleeve gastrectomy, there was a significant decrease in IOP measured 3-6 months after the procedure. Our results suggest that significant weight loss could have beneficial effects on IOP in obese individuals with ocular hypertension which might enable avoidance of antiglaucoma medications. The high likelihood of a reduction in IOP should be taken into account when considering bariatric surgery in such patients.
研究减重手术对眼内压（IOP）的影响。
我们前瞻性地招募了连续接受腹腔镜袖状胃切除术的肥胖患者。我们在手术前和术后 3-6 个月测量了 IOP，并记录了医疗和人口统计学参数。
32 例患者完成了所有评估。平均年龄为 40.5±12 岁，24 例（75%）为男性。手术后，平均体重指数（BMI）从 42±6 降至 31±8（p<0.001）。平均 IOP 从 16.9±4mmHg 降至 14.1±3mmHg（p<0.001）。IOP 降低的程度与基线 IOP（Pearson r=0.737，p<0.001）和中央角膜厚度（Pearson r=0.453，p=0.010）相关。
在接受袖状胃切除术的肥胖个体队列中，术后 3-6 个月测量的 IOP 显著降低。我们的结果表明，体重显著减轻可能对患有青光眼的肥胖个体的 IOP 产生有益影响，这可能使他们避免使用抗青光眼药物。在考虑此类患者进行减重手术时，应考虑到 IOP 降低的可能性很高。
