NIMBE, CEA, CNRS, Université Paris Saclay, CEA Saclay, 91191, Gif-sur-Yvette, France.
Laboratoire de Chimie de L'ENS LYON (UMR 5182), Ecole Normale Supérieure de Lyon, 46, Allée d'Italie, 69364, Lyon Cedex 07, France.
Chemistry. 2018 May 2;24(25):6534-6537. doi: 10.1002/chem.201800900. Epub 2018 Apr 16.
In the search for powerful non-invasive methods for pH measurement, NMR usually suffers from biases, especially for heterogeneous samples or tissues. In this Communication, using the signals of hyperpolarized Xe encapsulated in a pair of water-soluble cryptophanes, we show that a differential pH measurement can be achieved, free from most of these biases, by monitoring the difference between their chemical shifts.
在寻找强大的非侵入性 pH 测量方法时，NMR 通常受到偏差的影响，特别是对于不均匀的样品或组织。在本通讯中，我们使用一对水溶性隐穴包封的超极化 Xe 的信号，通过监测它们化学位移之间的差异，展示了一种可以实现免除此类大多数偏差的差分 pH 测量方法。
