Comparison of treatment with an Alexandrite picosecond laser and Nd:YAG nanosecond laser for removing blue-black Chinese eyeliner tattoos.

: To retrospectively evaluate the efficacy of an Alexandrite picosecond laser versus Nd:YAG nanosecond laser for removing blue-black eyeliner tattoos which have existed more than 10 years. : A total of 40 patients were treated with an Alexandrite picosecond laser in our department from August 2015 to July 2017, with a fluence of 1.96-6.37J/cm, spot size of 2.0-3.6 mm, and pulse width of 750 ps. Another 32 patients were treated with an Nd:YAG nanosecond laser, with a fluence of 2.80-7.00 J/cm, spot size of 3 mm, and pulse width of 5-20 ns. All analysed patients completed at least one treatment and follow-up. : The median number of treatment for all the patients was 1 (range, 1-4). After a single session, no difference was found between the two lasers for the eyeliner removal ( > 0.05). For the people who achieved an excellent response of tattoo clearance, there was still no difference between the two groups ( > 0.05). Transient side effects were observed in two groups, but neither group had significant adverse reactions. : To treat blue-black Chinese eyeliner tattoos over 10 years, Alexandrite picosecond laser does not provide better clearance than the Nd:YAG nanosecond laser.