支气管扩张症的最新进展。
Bronchiectasis update.
机构信息
Division of Pulmonary Critical Care and Sleep Medicine, Georgetown University Medical Center, Washington, District of Columbia, USA.
出版信息
Curr Opin Infect Dis. 2018 Apr;31(2):194-198. doi: 10.1097/QCO.0000000000000445.
PURPOSE OF REVIEW
Bronchiectasis, once thought to be an orphan disease, is being diagnosed with increased frequency in the United States and around the world. The present review aims to provide an update on recent publications on the diagnosis and management of bronchiectasis.
RECENT FINDINGS
Two large bronchiectasis patient registries have published initial reports regarding demographics and other patient data in 2017. Updates on the microbiology, microbiome, and inflammation in patients with bronchiectasis are clarifying the complexities of airway infection in this disease. A consensus definition of 'exacerbation' in bronchiectasis has been agreed upon this year. Reports on novel treatments, including the repurposing of older therapies, have also been published in 2016-2017. A new European guideline for the management of adult bronchiectasis is also now available.
SUMMARY
Bronchiectasis, a resurgent disease, is now being better defined with a rapidly expanding portfolio of demographic, clinical, and therapeutic research and publications.
目的综述
支气管扩张症曾被认为是一种罕见病，但现在在美国和世界各地的诊断频率都在增加。本综述旨在提供支气管扩张症诊断和治疗方面的最新文献更新。
最新发现
2017 年，两个大型支气管扩张症患者登记处发表了关于人口统计学和其他患者数据的初步报告。对支气管扩张症患者的微生物学、微生物组和炎症的更新，阐明了该疾病气道感染的复杂性。今年还就支气管扩张症“加重”达成了共识定义。2016-2017 年还发表了关于新型治疗方法的报告，包括旧疗法的再利用。目前也有新的欧洲成人支气管扩张症管理指南。
总结
支气管扩张症是一种重新出现的疾病，随着越来越多的人口统计学、临床和治疗研究和出版物的出现，其定义也在不断扩展。
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