Cingoz Ilker Deniz, Kizmazoglu Ceren, Guvenc Gonul, Sayin Murat, Imre Abdulkadir, Yuceer Nurullah
Department of Neurosurgery, Katip Çelebi University Ataturk Training and Research Hospital.
Department of Neurosurgery, Dokuz Eylul University School of Medicine.
J Craniofac Surg. 2018 Jun;29(4):1002-1005. doi: 10.1097/SCS.0000000000004398.
The aim of this study was to evaluate the olfactory function of patients who had undergone endoscopic transsphenoidal pituitary surgery. In this prospective study, the "Sniffin' Sticks" test was performed between June 2016 and April 2017 at Izmir Katip Celebi University Ataturk Training and Research Hospital. Thirty patients who were scheduled to undergo endoscopic transsphenoidal pituitary surgery were evaluated preoperatively and 8 weeks postoperatively using the Sniffin' Sticks test battery for olfactory function, odor threshold, smell discrimination, and odor identification. The patients were evaluated preoperatively by an otolaryngologist. The patients' demographic data and olfactory functions were analyzed with a t test and Wilcoxon-labeled sequential test. The study group comprised 14 women (46.7%) and 16 men (53.3%) patients. The mean age of the patients was 37.50 ± 9.43 years (range: 16-53 years). We found a significant difference in the preoperative and postoperative values of the odor recognition test (P = 0.017); however, there was no significant difference between the preoperative and postoperative odor threshold values (P = 0.172) and odor discrimination values (P = 0.624). The threshold discrimination identification test scores were not significant (P = 0.110). The olfactory function of patients who were normosmic preoperatively was not affected postoperatively. This study shows that the endoscopic transsphenoidal technique for pituitary surgery without nasal flap has no negative effect on the olfactory function.
本研究的目的是评估接受内镜经蝶窦垂体手术患者的嗅觉功能。在这项前瞻性研究中，于2016年6月至2017年4月在伊兹密尔卡迪普·切莱比大学阿塔图尔克培训与研究医院进行了“嗅觉棒”测试。对30例计划接受内镜经蝶窦垂体手术的患者在术前及术后8周使用“嗅觉棒”测试组进行嗅觉功能、气味阈值、气味辨别和气味识别评估。患者术前由耳鼻喉科医生进行评估。采用t检验和威尔科克森标记序贯检验对患者的人口统计学数据和嗅觉功能进行分析。研究组包括14名女性患者（46.7%）和16名男性患者（53.3%）。患者的平均年龄为37.50±9.43岁（范围：16 - 53岁）。我们发现气味识别测试的术前和术后值存在显著差异（P = 0.017）；然而，术前和术后的气味阈值（P = 0.172）和气味辨别值（P = 0.624）之间没有显著差异。阈值辨别识别测试分数无统计学意义（P = 0.110）。术前嗅觉正常的患者术后嗅觉功能未受影响。本研究表明，无鼻瓣的内镜经蝶窦垂体手术技术对嗅觉功能无负面影响。
