Ulici Alexandru, Florea Daniel-Catalin, Carp Madalina, Ladaru Alin, Tevanov Iulia
Department of Pediatric Orthopedic Surgery, Emergency Hospital for Children "Grigore Alexandrescu", 30-32, Iancu de Hunedoara Bvd, 011733, Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Int Orthop. 2018 Jun;42(6):1413-1419. doi: 10.1007/s00264-018-3841-y. Epub 2018 Feb 28.
Aneurysmal bone cyst (ABC) is a benign intraosseous lesion filled with blood that can determine a blowout distension of the bone. The purpose of this study is to evaluate the efficacy of sclerotherapy by percutaneous intralesional administration of ethanol 96% for the treatment of this pathology in paediatric patients.
The retrospective study includes 17 paediatric patients with ABC who were treated by repeated intracystic injection with ethanol 96%, 1 ml/kg, in our clinic between December 2015 and July 2017. Fluoroscopic guidance was used to inject the cyst with contrast agent. The mean follow-up period was 11 months.
All cysts are healed or are in the healing process. The mean age was 11 years old. Seven patients needed three repeated injections and ten patients needed two injections until healing. We observed a mean reduction in the size of the lesions, measured on plain X-rays, of 68%. The complications that were observed included the following: dizziness after injection, skin pigmentation at the injection site, local inflammatory reaction, and pain after injection. The current study approves the importance of this minimally invasive treatment with no recurrence after a follow-up of 19 months. The healing rate was 100%. A limitation of this study consists in the small number of patients.
Sclerotherapy with ethanol 96% is a useful method for the treatment of ABC. It is a minimally invasive method, with no major complications, which lowers the risks of open surgical intervention and has a good rate of success.
骨动脉瘤样囊肿（ABC）是一种充满血液的良性骨内病变，可导致骨的膨胀性扩张。本研究的目的是评估经皮瘤内注射96%乙醇硬化治疗小儿ABC的疗效。
回顾性研究纳入了2015年12月至2017年7月间在我院接受治疗的17例小儿ABC患者，采用96%乙醇1ml/kg反复囊内注射治疗。在透视引导下向囊肿内注射造影剂。平均随访时间为11个月。
所有囊肿均愈合或处于愈合过程中。平均年龄为11岁。7例患者需要3次反复注射，10例患者需要2次注射直至愈合。在X线平片上测量，病变大小平均缩小68%。观察到的并发症包括：注射后头晕、注射部位皮肤色素沉着、局部炎症反应和注射后疼痛。本研究证实了这种微创治疗的重要性，随访19个月后无复发。愈合率为100%。本研究的一个局限性在于患者数量较少。
96%乙醇硬化治疗是治疗ABC的一种有效方法。它是一种微创方法，无严重并发症，降低了开放手术干预的风险，成功率高。
