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[山东省女子强制隔离戒毒所女性吸毒人员单纯疱疹病毒2型感染及相关因素]

[Herpes simplex virus-2 infection and related factors among female drug abusers in the women's compulsory drug rehabilitation center of Shandong province].

作者信息

Duan Q, Li R, Liao M Z, Huang P X, Yu H Y, Yang T, Shan S X, Kang D M

机构信息

School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan 250062, China.

Shandong Center for Disease Control and Prevention, Jinan 250014, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Feb 10;39(2):199-203. doi: 10.3760/cma.j.issn.0254-6450.2018.02.012.

DOI:10.3760/cma.j.issn.0254-6450.2018.02.012
PMID:29495205
Abstract

This study aimed to understand the herpes simplex virus-2 (HSV-2) infection and related factors among female drug abusers in the women's compulsory drug rehabilitation center of Shandong province and to provide reference for the prevention and control of HSV-2 in these settings. We screened all of 451 female drug abusers in the women's compulsory drug rehabilitation centers in of Shandong province and conducted a study using both questionnaire investigation and serological tests for HSV-2, HIV and syphilis. We also used EpiData 3.1 software to establish a database and SPSS 20.0 software to conduct the (2) test and multivariate logistic regression analysis. A total of 451 female drug abusers were under study. We noticed that the rates for HSV-2 infection, HIV infection and syphilis infection appeared as 72.1% (325/451), 2.2% (10/451) and 33.5% (151/451) respectively. Results from univariate analysis showed that factors as: awareness on AIDS, having temporary sex partner after using the drug, having multiple sex partners after using the drug, providing commercial services or having temporary sex practice before being detained, with syphilis infection ., were associated with HSV-2 infection. Data from the multivariate analysis showed that the (95%) value of HSV-2 infection was 2.90 (1.19-7.06) for those who providing commercial service, when comparing to those who did not. Compared to those who did not suffer from syphilis infection, the (95%) value of HSV-2 infection for those with syphilis infection was 2.75 (1.63-4.63). The rate of HSV-2 infection was high in the women's compulsory drug rehabilitation center of Shandong province. We should enhance measures and promote condom use to prevent from HSV-2 and other sexually transmitted diseases among them.

摘要

本研究旨在了解山东省女子强制戒毒所女性吸毒人员单纯疱疹病毒2型(HSV-2)感染情况及相关因素,为该场所HSV-2的防控提供参考。我们对山东省女子强制戒毒所的451名女性吸毒人员进行了筛查,并采用问卷调查和HSV-2、HIV及梅毒血清学检测的方法开展研究。我们还使用EpiData 3.1软件建立数据库,并用SPSS 20.0软件进行检验和多因素logistic回归分析。共有451名女性吸毒人员参与研究。我们注意到,HSV-2感染率、HIV感染率和梅毒感染率分别为72.1%(325/451)、2.2%(10/451)和33.5%(151/451)。单因素分析结果显示,艾滋病知晓情况、吸毒后有临时性伴、吸毒后有多个性伴、被拘留前有商业性服务或临时性行为、感染梅毒等因素与HSV-2感染有关。多因素分析数据显示,与未提供商业性服务者相比,提供商业性服务者HSV-2感染的(95%)值为2.90(1.19 - 7.06)。与未感染梅毒者相比,感染梅毒者HSV-2感染的(95%)值为2.75(1.63 - 4.63)。山东省女子强制戒毒所HSV-2感染率较高。我们应加强措施并推广使用避孕套,以预防她们感染HSV-2及其他性传播疾病。

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