Delaney V, de Pertuz Y, Nixon D, Bourke E
Am J Kidney Dis. 1987 Jan;9(1):79-83. doi: 10.1016/s0272-6386(87)80166-x.
A 14-year-old female patient with metastatic carcinoid developed streptozocin-induced glomerular, proximal, and distal tubular dysfunction. The latter was in the form of nephrogenic diabetes insipidus, with urine volumes in excess of 11 L/24 h. The prostaglandin synthetase inhibitor, indomethacin, rapidly corrected the polyuria both initially and on rechallenge, independent of change in glomerular filtration rate.
一名患有转移性类癌的14岁女性患者出现了链脲佐菌素诱导的肾小球、近端和远端肾小管功能障碍。后者表现为肾性尿崩症，尿量超过11升/24小时。前列腺素合成酶抑制剂吲哚美辛在初始阶段和再次给药时均迅速纠正了多尿，且与肾小球滤过率的变化无关。
