Clifford P C, Gazzard V, Lawrance R J, Clyne C A, Webster J H
Ann R Coll Surg Engl. 1986 Nov;68(6):319-22.
This paper reports our preliminary experience using EXS Dacron for infrageniculate femoropopliteal grafts in elderly patients, the majority (78%) suffering critical ischaemia. A comparison is made with human umbilical vein grafts (HUV). Ninety patients (mean age 69 years) with 92 grafts (42 EXS, 50 HUV) were followed up using ultrasound imaging to detect patency (median follow up 26 weeks (range 1-292)). Two and one year cumulative survivals were 57% and 80% for EXS Dacron and 39% and 48% for HUV respectively. Early failure of HUV grafts accounted for most but not all of the difference in survival (P = 0.0012, Wilcoxon Breslow). Graft kinking was not seen in EXS grafts and in only 2 HUV. Poor calf vessel run off was related to early graft occlusion (P = 0.01; Savage, Mantel Cox). This preliminary experience with EXS Dacron is encouraging and suggests the need for a formal randomised study.
本文报告了我们在老年患者中使用EXS涤纶进行膝下股腘动脉移植的初步经验，这些患者大多数（78%）患有严重缺血。并与人体脐静脉移植物（HUV）进行了比较。对90例患者（平均年龄69岁）的92条移植物（42条EXS，50条HUV）进行了超声成像随访以检测通畅情况（中位随访26周（范围1 - 292周））。EXS涤纶移植物的两年和一年累积生存率分别为57%和80%，HUV移植物分别为39%和48%。HUV移植物的早期失败是生存率差异的主要但非全部原因（P = 0.0012，Wilcoxon Breslow检验）。EXS移植物未出现移植物扭结，仅2条HUV移植物出现扭结。小腿血管流出不良与移植物早期闭塞有关（P = 0.01；Savage，Mantel Cox检验）。EXS涤纶的这一初步经验令人鼓舞，并表明有必要进行正式的随机研究。
