理解细胞外基质以增强基于干细胞的组织再生。
Understanding the Extracellular Matrix to Enhance Stem Cell-Based Tissue Regeneration.
机构信息
Departments of Anesthesiology and Biomedical Engineering, Yale University, New Haven, CT 06520, USA.
出版信息
Cell Stem Cell. 2018 Mar 1;22(3):302-305. doi: 10.1016/j.stem.2018.02.001.
Abstract
The extracellular matrix is a biologically critical entity that has historically been poorly understood. Here we discuss how new tools for characterizing matrix composition and function enable us to design and deliver advanced matrices in vitro, to optimize regeneration, and in vivo, within a variety of tissues and organs.
摘要
细胞外基质是一种具有重要生物学意义的物质，但长期以来人们对其了解甚少。在这里，我们将讨论如何利用新的工具来描述基质的组成和功能，以便我们能够在体外设计和提供先进的基质，在体内优化组织和器官的再生。
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