Santhini P V, Smrithy A S, Irfana Jesin C P, Varughese Sunil, John Jubi, Radhakrishnan K V
Organic Chemistry Section, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram-19, India.
Chem Commun (Camb). 2018 Mar 25;54(24):2982-2985. doi: 10.1039/c7cc09521j. Epub 2018 Mar 5.
A Pd-catalyzed synthesis of 3,4,5-trisubstituted cyclopentenes from diazabicyclic olefins and o-iodobenzoates has been developed. The hitherto unknown cascade process involves three stages: carbopalladation, oxypalladation and a Tsuji-Trost reaction. We have also developed a facile route involving a novel benzylic C-H activation towards cyclopentenoindane moieties.
