Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, 2400, Copenhagen, Denmark.
Department of Occupational and Environmental Medicine, University of Copenhagen, Bispebjerg Hospital, 2400, Copenhagen, Denmark.
Contact Dermatitis. 2018 May;78(5):341-347. doi: 10.1111/cod.12934. Epub 2018 Mar 6.
Wet work is an important risk factor for occupational hand eczema.
To examine the effect of job change in workers with occupational hand eczema caused by wet work, and to evaluate the dose-response relationship between intensity of wet work and eczema.
The study is based on a subgroup (n = 954) from a descriptive, registry-based study including all participants with occupational hand eczema caused by wet work recognized by the Danish Labour Market Insurance Authority in 2010 and 2011. A follow-up questionnaire was sent out 4-5 years later (response 58%).
Change of profession and being outside the labour market had a positive effect on healing and improvement of hand eczema. Inverse dose-response relationships were found between the amount of time spent with wet hands at work and healing (p = 0.001) and improvement (p < 0.001), and between the frequency of hand washing at work and healing (p = 0.013) and improvement (p < 0.001).
Leaving the profession has a positive effect on eczema; however, even minor changes in exposure to wet work were associated with healing and improvement. This information has implications with respect to advice given to patients with occupational hand eczema caused by wet work.
湿工作是职业性手部湿疹的一个重要危险因素。
研究因湿工作导致手部湿疹的劳动者更换工作对湿疹的影响，并评估湿工作强度与湿疹之间的剂量-反应关系。
该研究基于一项描述性、基于登记的研究的亚组（n=954），包括 2010 年和 2011 年被丹麦劳动市场保险局认定为因湿工作导致手部湿疹的所有参与者。4-5 年后（应答率为 58%）发送了一份随访问卷。
职业变更和离开劳动力市场对手部湿疹的愈合和改善有积极影响。在工作中手部接触水的时间和洗手的频率与愈合（p=0.001）和改善（p<0.001）之间存在反向剂量-反应关系。
离开职业对手部湿疹有积极影响；然而，即使是对湿工作接触的微小改变，也与愈合和改善有关。这些信息对因湿工作导致手部湿疹的患者的建议有影响。
