Department of Dermatology, Bispebjerg University Hospital, 2400, Copenhagen, Denmark.
Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, 2400, Copenhagen, Denmark.
Contact Dermatitis. 2018 Jan;78(1):55-63. doi: 10.1111/cod.12869. Epub 2017 Oct 27.
Occupational hand eczema and/or contact urticaria may have social consequences such as change of profession or not remaining in the workforce.
To identify factors associated with job change in a cohort of participants with recognised occupational hand eczema/contact urticaria METHODS: A registry-based study including 2703 employees with recognised occupational hand eczema/contact urticaria in Denmark in 2010/2011. Four to five years later the participants received a follow-up questionnaire, comprising questions on current job situation (response rate 58.0%).
At follow-up, 51.3% of the participants were no longer in the same profession. 32.5% had changed profession and 18.8% were no longer in employment. Change of profession was associated with young age, positive patch test, low educational level and severity of hand eczema/contact urticaria. With regard to specific professions, cleaning personnel changed profession significantly more often than other workers [71.4% (OR = 2.26)], health care workers significantly less often than other workers [34.0% (OR = 0.36)].
Job change occurs frequently during the first years after recognition of occupational hand eczema/contact urticaria and more often among patients with positive patch test reactions, with severe hand eczema/contact urticaria. Whether job changes improve the prognosis of occupational hand eczema/contact urticaria remains to be established.
职业性手部湿疹和/或接触性荨麻疹可能会产生社交后果，例如改变职业或无法继续工作。
在丹麦，一项队列研究旨在确定与职业性手部湿疹/接触性荨麻疹患者职业变化相关的因素。
该研究为基于登记的研究，共纳入 2010/2011 年丹麦 2703 例确诊职业性手部湿疹/接触性荨麻疹的员工。四至五年后，参与者接受了随访问卷调查，其中包括当前工作状况的问题（应答率为 58.0%）。
随访时，51.3%的参与者不再从事相同的职业。32.5%的人换了职业，18.8%的人不再就业。职业变化与年龄较小、阳性斑贴试验、教育水平较低以及手部湿疹/接触性荨麻疹严重程度有关。就特定职业而言，清洁人员换职业的频率明显高于其他工人[71.4%（OR=2.26）]，医护人员换职业的频率明显低于其他工人[34.0%（OR=0.36）]。
在确诊职业性手部湿疹/接触性荨麻疹后的最初几年中，职业变化较为常见，且阳性斑贴试验反应、手部湿疹/接触性荨麻疹严重程度较重的患者更易发生职业变化。职业变化是否能改善职业性手部湿疹/接触性荨麻疹的预后尚待确定。
