系统神经科学方法治疗偏头痛。
A Systems Neuroscience Approach to Migraine.
机构信息
Department of Neurology, University of Utah, 383 Colorow Drive, Salt Lake City, UT 84108, USA.
Department of Biomedical Sciences and Padova Neuroscience Center, University of Padova, 35131 Padova, Italy; CNR Institute of Neuroscience, Via Ugo Bassi 58/B, 35131 Padova, Italy.
出版信息
Neuron. 2018 Mar 7;97(5):1004-1021. doi: 10.1016/j.neuron.2018.01.029.
Abstract
Migraine is an extremely common but poorly understood nervous system disorder. We conceptualize migraine as a disorder of sensory network gain and plasticity, and we propose that this framing makes it amenable to the tools of current systems neuroscience.
摘要
偏头痛是一种极其常见但尚未被充分了解的神经系统疾病。我们将偏头痛视为感觉网络增益和可塑性的障碍，并提出这种观点使其能够应用于当前系统神经科学的工具。
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本文引用的文献
1
Human models of migraine - short-term pain for long-term gain.偏头痛的人类模型——以短期疼痛换取长期获益。
Nat Rev Neurol. 2017 Dec;13(12):713-724. doi: 10.1038/nrneurol.2017.137. Epub 2017 Oct 6.
2
Amygdalar Gating of Early Sensory Processing through Interactions with Locus Coeruleus.通过与蓝斑的相互作用实现杏仁核早期感觉加工的门控作用。
J Neurosci. 2017 Mar 15;37(11):3085-3101. doi: 10.1523/JNEUROSCI.2797-16.2017. Epub 2017 Feb 10.
3
Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms.外周和中枢降钙素基因相关肽机制均可诱导小鼠出现偏头痛样畏光行为。
J Neurosci. 2017 Jan 4;37(1):204-216. doi: 10.1523/JNEUROSCI.2967-16.2016.
4
Structural alterations of the brainstem in migraine.偏头痛中脑干的结构改变。
Neuroimage Clin. 2016 Nov 2;13:223-227. doi: 10.1016/j.nicl.2016.10.023. eCollection 2017.
5
Structural plasticity and reorganisation in chronic pain.慢性疼痛中的结构可塑性和重组。
Nat Rev Neurosci. 2016 Dec 15;18(1):20-30. doi: 10.1038/nrn.2016.162.
6
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Neuron. 2016 Nov 23;92(4):739-753. doi: 10.1016/j.neuron.2016.10.015. Epub 2016 Oct 27.
7
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